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Inhibitory effect of orthokeratology on myopic progression in monkeys

Research Project

Project/Area Number 21592254
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionUniversity of Tsukuba

Principal Investigator

HIRAOKA Takahiro  筑波大学, 医学医療系, 講師 (30359575)

Co-Investigator(Kenkyū-buntansha) KAJI Yuichi  筑波大学, 医学医療系, 准教授 (50361332)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥130,000 (Direct Cost: ¥100,000、Indirect Cost: ¥30,000)
Fiscal Year 2010: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2009: ¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Keywords近視 / オルソケラトロジー / 眼軸長 / 波面収差
Research Abstract

We clarified that orthokeratology can suppress myopic progression in childhood myopia. Our results confirmed that axial elongation was significantly smaller in the orthokeratology group than in the spectacle control group. The inhibitory effect was most noticeable over the first year of orthokeratology treatment and decreased with time. The details of these results were summarized in the following two articles. (Kakita T, Hiraoka T, Oshika T. Influence of overnight orthokeratology on axial elongation in childhood myopia. Invest Ophthalmol Vis Sci. 2011 ; 52:2170-4), (Hiraoka T, Kakita T, Okamoto F, Takahashi H, Oshika T. Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia : a 5-year follow-up study. Invest Ophthalmol Vis Sci. 2012 ; Epub ahead of print).

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (55 results)

All 2012 2011 2010 2009

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (36 results) Book (7 results)

  • [Journal Article] Long-term effect of overnight orthokeratology on axial length elongation in childhood myopia : a 5-year follow-up study2012

    • Author(s)
      Hiraoka T, Kakita T, Okamoto F, Takahashi H, Oshika T
    • Journal Title

      Invest Ophthalmol Vis Sci

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Influence of overnight orthokeratology on axial elongation in childhood myopia2011

    • Author(s)
      Kakita T, Hiraoka T, Oshika T
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 52 Pages: 2170-2174

    • NAID

      120007137373

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] オルソケラトロジーによる角膜後面形状変化の経時的評価2011

    • Author(s)
      平岡孝浩, 加治優一, 岡本史樹, 大鹿哲郎
    • Journal Title

      日本コンタクトレンズ学会誌

      Volume: 53 Pages: 7-11

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Time course of changes in ocular aberrations after instillation of carteolol long-acting solution and timolol gel-forming solution2011

    • Author(s)
      Hiraoka Takahiro
    • Journal Title

      J Ocul Pharmacol Ther

      Volume: 27 Issue: 2 Pages: 179-185

    • DOI

      10.1089/jop.2010.0149

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Time course of changes in functional visual acuity and ocular wavefront aberration after instillation of ofloxacin gel-forming ophthalmic solution2011

    • Author(s)
      Yamamoto Toshiya, Hiraoka Takahiro, Oshika Tetsuro
    • Journal Title

      Nihon Ganka Gakkai Zasshi

      Volume: 115 Pages: 1094-1100

    • NAID

      10030248935

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of overnight orthokeratology on axial length elongation in childhood myopia2011

    • Author(s)
      Kakita Tetsuhiko
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: Epub ahead of print

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] オルソケラトロジーの原理と角膜形状変化2010

    • Author(s)
      平岡孝浩
    • Journal Title

      あたらしい眼科

      Volume: 27 Pages: 1493-1499

    • NAID

      10028246552

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 就寝時装用オルソケラトロジーレンズの臨床評価2010

    • Author(s)
      平岡孝浩
    • Journal Title

      日本コンタクトレンズ学会誌

      Volume: 52

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of induced decentered orthokeratology lens on ocular higher-order wavefront aberrations and contrast sensitivity function.2009

    • Author(s)
      Hiraoka Takahiro
    • Journal Title

      J Cataract Refract Surg VOL.35

      Pages: 1918-1926

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Corneal sensation after overnight orthokeratology.2009

    • Author(s)
      Hiraoka Takahiro
    • Journal Title

      Cornea VOL.28

      Pages: 891-895

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Patient satisfaction and clinical outcomes after overnight orthokeratology.2009

    • Author(s)
      Hiraoka Takahiro
    • Journal Title

      Optom Vis Sci VOL.86

      Pages: 875-882

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Recovery of corneal irregular astigmatism, ocular higher-order aberrations, and contrast sensitivity after discontinuation of overnight orthokeratology.2009

    • Author(s)
      Hiraoka Takahiro
    • Journal Title

      Br J Ophthalmol VOL.93

      Pages: 203-208

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Statistical Analysis of Post-marketing Surveillance of Overnight Orthokeratology For Two Years In Japan2012

    • Author(s)
      Hiraoka T
    • Organizer
      3rd Asia Orthokeratology and Specialty Lens Conference (Symposium)
    • Place of Presentation
      Haiwaihai International Convention & Exhibition Center (Hangzhou, China)
    • Year and Date
      2012-03-31
    • Related Report
      2011 Final Research Report
  • [Presentation] Statistical Analysis Of Post-marketing Surveillance Of Overnight Orthokeratology For Two Years In Japan2012

    • Author(s)
      Hiraoka Takahiro
    • Organizer
      3rd Asia Orthokeratology and Specialty Lens Conference (Symposium)
    • Place of Presentation
      Haiwaihai International Convention & Exhibition Center (Hangzhou, China)(招待講演)
    • Year and Date
      2012-03-31
    • Related Report
      2011 Annual Research Report
  • [Presentation] Long-term Effect of Overnight Orthokeratology on Axial Length Elongation in Childhood Myopia : A 5-year Follow-up Study in Japan2012

    • Author(s)
      Hiraoka T
    • Organizer
      2012CLAO/CLAO ERF Symposium and Congress
    • Place of Presentation
      Caesars Palace Hotel (Las Vegas, NV)
    • Year and Date
      2012-01-27
    • Related Report
      2011 Final Research Report
  • [Presentation] Long-term Effect of Overnight Orthokeratology on Axial Length Elongation in Childhood Myopia : A 5-year Follow-up Study in Japan2012

    • Author(s)
      Hiraoka Takahiro
    • Organizer
      2012 CLAO/CLAO ERF Symposium and Congress
    • Place of Presentation
      Caesars Palace Hotel (Las Vegas, NV)(招待講演)
    • Year and Date
      2012-01-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] オーバーナイトオルソケラトロジー長期装用が眼軸長変化に及ぼす影響.日本人学童における5年間経過観察結果2011

    • Author(s)
      平岡孝浩
    • Organizer
      第1回アジア・メディカル・コンタクトレンズ・セミナー
    • Place of Presentation
      京都
    • Year and Date
      2011-11-13
    • Related Report
      2011 Final Research Report
  • [Presentation] オーバーナイトオルソケラトロジー長期装用が眼軸長変化に及ぼす影響.日本人学童における5年間経過観察結果2011

    • Author(s)
      平岡孝浩
    • Organizer
      第1回アジア・メディカル・コンタクトレンズ・セミナー
    • Place of Presentation
      京都テルサ(京都府)(招待講演)
    • Year and Date
      2011-11-13
    • Related Report
      2011 Annual Research Report
  • [Presentation] 合併症と対処法2011

    • Author(s)
      平岡孝浩
    • Organizer
      第65回日本臨床眼科学会総会(オルソケラトロジー講習会)
    • Place of Presentation
      東京
    • Year and Date
      2011-10-10
    • Related Report
      2011 Final Research Report
  • [Presentation] オルソケラトロジー講習会 合併症と対処法2011

    • Author(s)
      平岡孝浩
    • Organizer
      第65回日本臨床眼科学会総会
    • Place of Presentation
      東京国際フォーラム(東京都)(招待講演)
    • Year and Date
      2011-10-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 近視進行予防の最前線.オルソケラトロジーによる近視進行防止2011

    • Author(s)
      平岡孝浩
    • Organizer
      第65回日本臨床眼科学会総会(シンポジウム)
    • Place of Presentation
      東京
    • Year and Date
      2011-10-08
    • Related Report
      2011 Final Research Report
  • [Presentation] 近視進行予防の最前線.オルソケラトロジーによる近視進行防止2011

    • Author(s)
      平岡孝浩
    • Organizer
      第65回日本臨床眼科学会総会
    • Place of Presentation
      東京国際フォーラム(東京都)(シンポジウム)(招待講演)
    • Year and Date
      2011-10-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] 合併症と対処法2011

    • Author(s)
      平岡孝浩
    • Organizer
      第54回日本コンタクトレンズ学会総会(オルソケラトロジー講習会)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-10
    • Related Report
      2011 Final Research Report
  • [Presentation] オルソケラトロジー講習会 合併症と対処法2011

    • Author(s)
      平岡孝浩
    • Organizer
      第54回日本コンタクトレンズ学会総会
    • Place of Presentation
      国立京都国際会館(京都府)(招待講演)
    • Year and Date
      2011-07-10
    • Related Report
      2011 Annual Research Report
  • [Presentation] 各種コンタクトレンズが眼光学系と視覚の質に及ぼす影響2011

    • Author(s)
      平岡孝浩
    • Organizer
      第54回日本コンタクトレンズ学会総会(日本コンタクトレンズ学会学術奨励賞講演)
    • Place of Presentation
      京都
    • Year and Date
      2011-07-09
    • Related Report
      2011 Final Research Report
  • [Presentation] 日本コンタクトレンズ学会学術奨励賞受賞講演 各種コンタクトレンズが眼光学系と視覚の質に及ぼす影響2011

    • Author(s)
      平岡孝浩
    • Organizer
      第54回日本コンタクトレンズ学会総会
    • Place of Presentation
      国立京都国際会館(京都府)(招待講演)
    • Year and Date
      2011-07-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] 合併症と対処法2011

    • Author(s)
      平岡孝浩
    • Organizer
      第115回日本眼科学会総会(オルソケラトロジー講習会)
    • Place of Presentation
      東京
    • Year and Date
      2011-05-15
    • Related Report
      2011 Final Research Report
  • [Presentation] オルソケラトロジー講習会 合併症と対処法2011

    • Author(s)
      平岡孝浩
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム(東京都)(招待講演)
    • Year and Date
      2011-05-15
    • Related Report
      2011 Annual Research Report
  • [Presentation] 5年間のオルソケラトロジー治療継続が小児期の眼軸長変化に及ぼす影響2011

    • Author(s)
      平岡孝浩, 柿田哲彦, 大鹿哲郎
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      東京
    • Year and Date
      2011-05-12
    • Related Report
      2011 Final Research Report
  • [Presentation] 5年間のオルソケラトロジー治療継続が小児期の眼軸長変化に及ぼす影響2011

    • Author(s)
      平岡孝浩
    • Organizer
      第115回日本眼科学会総会
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2011-05-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] Influence of overnight orthokeratology on axial length elongation in childhood myopia. (Symposium)2011

    • Author(s)
      Hiraoka Takahiro
    • Organizer
      The 11^<th> International Congress of Ophthalmology and Optometry China (COOC 2011)
    • Place of Presentation
      Shanghai Everbright Convention & Exhibition Center (Shanghai, China)(招待講演)
    • Year and Date
      2011-04-08
    • Related Report
      2011 Annual Research Report
  • [Presentation] Influence of overnight orthokeratology on axial length elongation in childhood myopia. (Symposium)2011

    • Author(s)
      Hiraoka T
    • Organizer
      The 11^<th> International Congress of Ophthalmology and Optometry China (COOC 2011)
    • Place of Presentation
      Shanghai, China
    • Year and Date
      2011-04-04
    • Related Report
      2011 Final Research Report
  • [Presentation] T : Higher-Order Aberrations InVarious Ocular Conditions.Higher-order aberrations during orthokeratology. (Symposium)2011

    • Author(s)
      Hiraoka T
    • Organizer
      Asia Pacific Academy of Ophthalmology Congress (APAO Sydney 2011)
    • Place of Presentation
      Sydney, Australia
    • Year and Date
      2011-03-23
    • Related Report
      2011 Final Research Report
  • [Presentation] Higher-Order Aberrations and Quality of Vision during Overnight Orthokeratology2011

    • Author(s)
      Hiraoka Takahiro
    • Organizer
      Asia Pacific Academy of Ophthalmology Congress 2011
    • Place of Presentation
      Sydney Convention and Exhibition Centre (Sydney, Australia)
    • Year and Date
      2011-03-23
    • Related Report
      2010 Annual Research Report
  • [Presentation] Quality of Vision and Higher-Order Aberrations after Overnight Orthokeratology2010

    • Author(s)
      Hiraoka T
    • Organizer
      2^<nd> AsiaOrthokeratology and Specialty Lens Conference (Symposium)
    • Place of Presentation
      Kyoto, Japan
    • Year and Date
      2010-12-03
    • Related Report
      2011 Final Research Report
  • [Presentation] Quality of Vision and Higher-Order Aberrations after Ovemight Orthokeratology2010

    • Author(s)
      Hiraoka Takahiro
    • Organizer
      2^<nd> Asia Orthokeratology and Specialty Lens Conference
    • Place of Presentation
      The Westin Miyako Kyoto (Kyoto, Japan)
    • Year and Date
      2010-12-03
    • Related Report
      2010 Annual Research Report
  • [Presentation] 合併症と対処法2010

    • Author(s)
      平岡孝浩
    • Organizer
      第64回日本臨床眼科学会総会(オルソケラトロジー講習会)
    • Place of Presentation
      神戸
    • Year and Date
      2010-11-14
    • Related Report
      2011 Final Research Report
  • [Presentation] オルソケラトロジーの長期臨床経過2010

    • Author(s)
      星崇仁, 平岡孝浩, 大鹿哲郎, 佐藤裕也
    • Organizer
      第64回日本臨床眼科学会総会
    • Place of Presentation
      神戸
    • Year and Date
      2010-11-14
    • Related Report
      2011 Final Research Report
  • [Presentation] 第5回オルソケラトロジー講習会合併症と対処法2010

    • Author(s)
      平岡孝浩
    • Organizer
      第64回日本臨床眼科学会総会
    • Place of Presentation
      神戸ポートピアホテル(兵庫県)
    • Year and Date
      2010-11-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 処方の手順2010

    • Author(s)
      平岡孝浩
    • Organizer
      第53回日本コンタクトレンズ学会総会(オルソケラトロジー講習会)
    • Place of Presentation
      東京
    • Year and Date
      2010-07-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 第4回オルソケラトロジー講習会処方の手順2010

    • Author(s)
      平岡孝浩
    • Organizer
      第53回日本コンタクトレンズ学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2010-07-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] オルソケラトロジーによる角膜後面形状変化の経時的評価2010

    • Author(s)
      平岡孝浩, 加治優一, 岡本史樹, 大鹿哲郎
    • Organizer
      第53回日本コンタクトレンズ学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-07-10
    • Related Report
      2011 Final Research Report
  • [Presentation] オルソケラトロジーによる角膜後面形状変化の経時的評価2010

    • Author(s)
      平岡孝浩
    • Organizer
      第53回日本コンタクトレンズ学会総会
    • Place of Presentation
      京王プラザホテル(東京都)
    • Year and Date
      2010-07-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 処方の手順2010

    • Author(s)
      平岡孝浩
    • Organizer
      第114回日本眼科学会総会(オルソケラトロジー講習会)
    • Place of Presentation
      東京
    • Year and Date
      2010-04-18
    • Related Report
      2011 Final Research Report
  • [Presentation] 第3回オルソケラトロジー講習会処方の手順2010

    • Author(s)
      平岡孝浩
    • Organizer
      第114回日本眼科学会総会
    • Place of Presentation
      名古屋国際会議場(愛知県)
    • Year and Date
      2010-04-18
    • Related Report
      2010 Annual Research Report
  • [Presentation] オルソケラトロジーの可能性と限界.2009

    • Author(s)
      平岡孝浩
    • Organizer
      平成21年度第1回千葉県眼科医会学術講演会
    • Place of Presentation
      幕張メッセ(千葉県)
    • Year and Date
      2009-07-12
    • Related Report
      2009 Annual Research Report
  • [Presentation] オルソケラトロジーによる近視矯正.-日本初の認可:オルソ-K-国内臨床試験の成績.2009

    • Author(s)
      平岡孝浩
    • Organizer
      第52回日本コンタクトレンズ学会総会
    • Place of Presentation
      グランキューブ大阪(大阪府)
    • Year and Date
      2009-07-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] オルソケラトロジーとQuality of Vision.2009

    • Author(s)
      平岡孝浩
    • Organizer
      第48回日本白内障学会総会,第24回日本眼内レンズ屈折手術学会絵会,第45回日本眼光学会総会,22nd APACRS Annual Meeting
    • Place of Presentation
      東京国際フォーラム(東京都)
    • Year and Date
      2009-06-26
    • Related Report
      2009 Annual Research Report
  • [Book] コンタクトレンズ自由自在2011

    • Author(s)
      平岡孝浩(大橋裕一, 編)
    • Publisher
      中山書店
    • Related Report
      2011 Final Research Report
  • [Book] 眼科学第2版2011

    • Author(s)
      平岡孝浩
    • Publisher
      文光堂
    • Related Report
      2011 Final Research Report
  • [Book] 眼科学 第2版 オルソケラトロジー2011

    • Author(s)
      平岡孝浩
    • Publisher
      文光堂
    • Related Report
      2011 Annual Research Report
  • [Book] 専門医のための眼科診療クオリファイ6 コンタクトレンズ自由自在 オルソケラトロジーに挑戦する.処方の実際2011

    • Author(s)
      平岡孝浩
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report
  • [Book] 専門医のための眼科診療クオリファイ6 コンタクトレンズ自由自在 オルソケラトロジーで近視の進行は抑制できますか?2011

    • Author(s)
      平岡孝浩
    • Publisher
      中山書店
    • Related Report
      2011 Annual Research Report
  • [Book] 眼科ケア12はじめてのオルソケラトロジーQ & A2010

    • Author(s)
      平岡孝浩
    • Publisher
      メディカ出版
    • Related Report
      2011 Final Research Report
  • [Book] 眼科ケア はじめてのオルソケラトロジー 処方の手順とチェックポイント2010

    • Author(s)
      平岡孝浩
    • Publisher
      (株)メディカ出版
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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