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Comprehensive evaluation of corneal optical characteristics using new generation optical coherence tomography

Research Project

Project/Area Number 21592257
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Ophthalmology
Research InstitutionOsaka University

Principal Investigator

MAEDA Naoyuki  大阪大学, 医学系・研究科, 寄附講座教授 (00273623)

Co-Investigator(Kenkyū-buntansha) FUJIKADO Takashi  大阪大学, 医学系研究科, 教授 (50243233)
井上 智之  大阪大学, 医学系研究科, 助教 (50432539)
Co-Investigator(Renkei-kenkyūsha) HORI Yuichi  東邦大学, 医学部, 講師 (70379171)
Research Collaborator INOUE Tomoyuki  財団法人住友病院, 眼科診療, 部長
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
Keywords眼光学 / 視覚の質 / 収差 / 散乱 / 光干渉断層計
Research Abstract

Corneal optical characteristics in normal eyes, keratoconus, post-keratoplasty, and LASIK were comprehensively investigated not only with conventional corneal topographers and wavefront sensor but also with OCT topographer that was newly developed in the study. The results indicated that the trends in corneal higher-order aberrations for each category showed unique pattern. The OCT based-corneal topographic analysis was successfully developed. The results of OCT corneal topographer were similar to that with conventional methods. In addition, its results were more precise than that with conventional methods in severe keratoconus.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (15 results)

All 2012 2011 2010 2009

All Journal Article (9 results) (of which Peer Reviewed: 9 results) Presentation (4 results) Book (2 results)

  • [Journal Article] Characteristic Higher-Order Aberrations of the Anterior and Posterior Corneal Surfaces in 3 Corneal Transplantation Techniques2012

    • Author(s)
      Koh S, Maeda N, Nakagawa T, Higashiura R, Saika M, Mihashi T, Fujikado T, Nishida K
    • Journal Title

      Am J Ophthalmol

      Volume: 153 Pages: 284-290

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Corneal topographic analysis in patients with keratoconus using 3-dimensional anterior segment optical coherence tomography2011

    • Author(s)
      Tomoya Nakagawa, Naoyuki Maeda, Ritsuko Higashiura, Yuichi Hori, Tomoyuki Inoue, Kohji Nishida
    • Journal Title

      J Cataract Refract Surg

      Volume: 37 Pages: 1871-1878

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Optical Coherence Tomography for Corneal Diseases2010

    • Author(s)
      Naoyuki Maeda
    • Journal Title

      Eye & Contact Lens

      Volume: 5 Pages: 254-259

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Optical Coherence Tomography for Corneal Diseases.2010

    • Author(s)
      Naoyuki Maeda
    • Journal Title

      Eye & Contact Lens

      Volume: 5 Pages: 254-259

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of NIDEK optimized aspheric transition zone ablation profile on higher order aberrations during LASIK for myopia2009

    • Author(s)
      Ryo Kosaki, Naoyuki maeda, Hitoshi Hayashi, Takashi Fujikado, Shigeki Okamoto
    • Journal Title

      J Refract Surg

      Volume: 25 Pages: 331-338

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Higher-Order Aberrations due to the Posterior Corneal Surface in Patients with Keratoconus2009

    • Author(s)
      Tomoya Nakagawa, Naoyuki Maeda, Ryo Kosaki, Yuichi Hori, Tomoyuki Inoue, Makoto Saika, Toshifumi Mihashi, Takashi Fujikado, Yasuo Tano
    • Journal Title

      Invest Ophthalmol Vis Sci

      Volume: 50 Pages: 2660-2665

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Higher-Order Aberrations due to the Posterior Corneal Surface in Patients with Keratoconus2009

    • Author(s)
      Nakagawa T, et al
    • Journal Title

      Invest Ophthalmol Vis Sci 50

      Pages: 2660-2665

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effect of NIDEK optimized aspheric transition zone ablation profile on higher order aberrations during LASIK for myopia2009

    • Author(s)
      Kosaki R, et al
    • Journal Title

      J Refract Surg 25

      Pages: 331-338

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Clinical application of wavefront aberrometry-A review2009

    • Author(s)
      Maeda N
    • Journal Title

      Clinical & Experimental Ophthalmology 37

      Pages: 118-129

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Corneal imaging using three-dimensional anterior segment OCT2012

    • Author(s)
      Naoyuki Maeda
    • Organizer
      World Ophthalmology Congress 2012
    • Place of Presentation
      Abu Dhabi, UAE
    • Year and Date
      2012-02-18
    • Related Report
      2011 Final Research Report
  • [Presentation] Advances in anterior segment OCT and wavefront technology2011

    • Author(s)
      Naoyuki Maeda
    • Organizer
      28^<th> Scientific meeting The Royal College of Ophthalmologist of Thailand
    • Place of Presentation
      Bangkok, Thailand
    • Year and Date
      2011-12-07
    • Related Report
      2011 Final Research Report
  • [Presentation] OCT imaging in corneal diseases2011

    • Author(s)
      Naoyuki Maeda
    • Organizer
      American Academy of Ophthalmology Annual Meeting
    • Place of Presentation
      Orlando, Florida, USA.
    • Year and Date
      2011-10-24
    • Related Report
      2011 Final Research Report
  • [Presentation] OCT-based corneal topography2011

    • Author(s)
      Naoyuki Maeda
    • Organizer
      Association for Research in Vision and Ophthalmology annual meeting
    • Place of Presentation
      Fort Lauderdale, USA
    • Year and Date
      2011-05-03
    • Related Report
      2011 Final Research Report
  • [Book] Topcon KR-1W. In : Corneal topography : A guide for clinical application in the wavefront era 2nd Ed.(Ed, M. Wang)2012

    • Author(s)
      Naoyuki Maeda
    • Publisher
      SLACK Incorporated, Thorofare
    • Related Report
      2011 Final Research Report
  • [Book] Evaluation of Corneal Optical Quality for Premium IOLs with Pentacam HR. In : Elevation based corneal tomography(Ed, Belin MW, Khachikian SS, Ambrosio R)2011

    • Author(s)
      Naoyuki Maeda
    • Publisher
      Jaypee-Highlights Medical Publishers, Inc., Panama
    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

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