| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Research Abstract |
Retinal degeneration models as were studied as a host for the acceptability of transplanted cells. Graft cells survived best when transplanted within a period of after the massive cell death and before the host gliosis progresses. In this time window, anti-inflammatory reagent and a synaptogenic factor enhanced graft cell(neonatal retinal cells) survival, and anti-gliotic reagent enhanced graft cell survival in later transplantation. We also prepared ES/iPS derived retinal cells for future practical transplantation experiments.
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