Histological study for mechanosensitive channels in the supratarsal Mueller' s muscle of upper eyelid
| Project/Area Number |
21592284
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Shinshu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MATSUO Kiyoshi 信州大学, 医学部, 教授 (20135156)
FUJITA Kenya 信州大学, 医学部附属病院, 講師 (00447781)
YANO Shiharu 信州大学, 医学部附属病院, 助教(診療) (10531907)
BAN Ryokuya 信州大学, 医学部, 助教 (30447784)
MISHIMA Yoshito 信州大学, 医学部附属病院, 助教(診療) (80464098)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,730,000 (Direct Cost: ¥2,100,000、Indirect Cost: ¥630,000)
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| Keywords | 上眼瞼 / ミュラー筋 / 機械刺激受容 / カハール介在細胞 / ICC / 平滑筋 / 神経線維 / 免疫組織化学 / 整経線維 / 機械刺激受容チャネル / TRP |
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| Research Abstract |
Mueller's muscle is a smooth muscle tissue on the margin of eyelid. It is contracted by stimulation of the sympathetic nerve. It is not only one of the muscle elevating upper eyelid but also a mechanoreceptor to contract the levator palpebral muscle which is a main eye opening skeletal muscle innervated by oculomotor nerve. In this histological study, we found mechanosensitive channels at the nerve ending and smooth muscle cells in Mueller' s muscle. And, we also found interstitial cells of Cajal mediating neurotransmission between nerve and smooth muscle in Mueller' s muscle like in the bladder and gastrointestinal tract.
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Report
(4 results)
Research Products
(5 results)
