Study of the prevention of denervation muscle atrophy by using in-flow type end-to-side neurrhaphy
| Project/Area Number |
21592291
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Plastic surgery
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| Research Institution | Fukushima Medical University |
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Principal Investigator |
UEDA Kazuki 福島県立医科大学, 医学部, 教授 (40160163)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Keywords | 神経科学 / 脱神経性萎縮 / 端側型神経縫合 / 神経端側縫合 / 脱神経性委縮 / 筋肉 |
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| Research Abstract |
The purpose of this study is to clarify whether flow-in end-to-side nerve anastomosis can prevent denervation atrophy of the muscle. In rats, the zygomatic branch was anastomosed with the side of the buccal branch, which was cut and immediately sutured at one or two portions proximal to the anastomotic site. Then, after the some period, the zygomatic branch was cut(donor release). As a result, the number of the regenerated axons was less distally than proximally to the anastomotic site in the one-portion-cut group, while it was more distally than proximally in the two-portions-cut group. It is recommended that flow-in end-to-side nerve anastomosis accompanied by donor release is recommended only for the nerve with severe damage
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Report
(4 results)
Research Products
(2 results)
