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Study of the prevention of denervation muscle atrophy by using in-flow type end-to-side neurrhaphy

Research Project

Project/Area Number 21592291
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Plastic surgery
Research InstitutionFukushima Medical University

Principal Investigator

UEDA Kazuki  福島県立医科大学, 医学部, 教授 (40160163)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywords神経科学 / 脱神経性萎縮 / 端側型神経縫合 / 神経端側縫合 / 脱神経性委縮 / 筋肉
Research Abstract

The purpose of this study is to clarify whether flow-in end-to-side nerve anastomosis can prevent denervation atrophy of the muscle. In rats, the zygomatic branch was anastomosed with the side of the buccal branch, which was cut and immediately sutured at one or two portions proximal to the anastomotic site. Then, after the some period, the zygomatic branch was cut(donor release). As a result, the number of the regenerated axons was less distally than proximally to the anastomotic site in the one-portion-cut group, while it was more distally than proximally in the two-portions-cut group. It is recommended that flow-in end-to-side nerve anastomosis accompanied by donor release is recommended only for the nerve with severe damage

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (2 results)

All 2011

All Presentation (2 results)

  • [Presentation] 流入型神経端側縫合の実験的検討に関するdonor releaseの影響2011

    • Author(s)
      桑田知幸、上田和毅、梶川明義、大河内真之、望月靖史、大河内裕美、阪場貴夫、桑田久美子
    • Organizer
      第20回日本形成外科学会基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-06
    • Related Report
      2011 Final Research Report
  • [Presentation] 流入型神経端側縫合の実験的検討~donor releaseの影響~2011

    • Author(s)
      桑田知行、上田和毅
    • Organizer
      第20回日本形成外科学会基礎学術集会
    • Place of Presentation
      東京
    • Year and Date
      2011-10-06
    • Related Report
      2011 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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