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Morphological analysis of cementogenesis using a newly identified cementoblast specific marker

Research Project

Project/Area Number 21592322
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Morphological basic dentistry
Research InstitutionNiigata University

Principal Investigator

KAWANO Yoshiro  新潟大学, 医歯学系, 助教 (60303129)

Co-Investigator(Kenkyū-buntansha) MAEDA Takeyasu  新潟大学, 医歯学系, 教授 (40183941)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Keywords歯根形成 / アクアポリン / セメント質 / 顕微解剖学 / 免疫組織化学
Research Abstract

We demonstrated the expression of aquaporin during cementgenesis. Cells on the developing root surface expressed aquaporin in rat molars during acellular cementgenesis. We immuno-histochemicaly identified these cells as cementblasts. The expression of aquaporin was observed on the cells on the interface between periodontal ligament and alveolar bone during alveolar bone development. These cells showed the different shapes from cementoblasts and possessed wing-like projections. These results suggest that aquapolin plays an important role during the development of periodontal tissue.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (21 results)

All 2011 2010 2009

All Journal Article (4 results) (of which Peer Reviewed: 4 results) Presentation (16 results) Book (1 results)

  • [Journal Article] Detection of acid-sensing ion chancel 3(ASIC3) in periodontal Ruffini endings of mouse incisors2011

    • Author(s)
      Rahman F, Harada F, Saito I, Suzuki A, Kawano Y, Izumi K, Nozawa-Inoue K, Maeda T
    • Journal Title

      Neurosci. Lett

      Volume: 488(2) Pages: 173-177

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phenotypes of articular disc cells in the rat temporomandibular joint as demonstrated by immunohistochemistry for nestin and GFAP2011

    • Author(s)
      Miyako H, Suzuki A, Nozawa-Inoue K, Magara J, Kawano Y, Ono K, Maeda T.
    • Journal Title

      J. Anat

      Volume: 219(4) Pages: 472-480

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Immunohistochemical detection of nestin in the periodontal Ruffini endings of the rat incisor2009

    • Author(s)
      Saito S, Suzuki A, Nozawa-Inoue K, Kawano Y, Hoshino M, Saito C, Maeda T
    • Journal Title

      Neurosci. Lett

      Volume: 449 Pages: 195-200

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Differential cell-specific location of Cav-1 and Ca^2+ATPase in terminal Schwann cells and mechanoreceptive Ruffini endings in the periodontal ligament of the rat incisor2009

    • Author(s)
      Iizuka N, Suzuki A, Nozawa-Inoue K, Kawano Y, Nandasena BGTL, Okiji T, Maeda T
    • Journal Title

      J. Anat

      Volume: 214(2) Pages: 264-274

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Presentation] Reaction of AQP-1 positive cells in rat periodontal ligament during experimental tooth movement2011

    • Author(s)
      Anwar Humayra Binte
    • Organizer
      平成23年度新潟歯学会第2回例会
    • Place of Presentation
      新潟
    • Year and Date
      2011-11-12
    • Related Report
      2011 Final Research Report
  • [Presentation] Reaction of AQP1 positive cells in rat periodontal ligament during experimental tooth movement2011

    • Author(s)
      Anwar Humayra Binte, 河野芳朗, 木下-河野承子, 野澤-井上佳世子, 斎藤功, 前田健康
    • Organizer
      平成23年度新潟歯学会第2例会
    • Place of Presentation
      新潟市新潟大学歯学部(招待講演)
    • Year and Date
      2011-11-12
    • Related Report
      2011 Annual Research Report
  • [Presentation] 実験的矯正移動にともなうアクアポリン1陽性細胞の観察2011

    • Author(s)
      Anwar Humayra Binte
    • Organizer
      第53回歯科基礎医学会学術大会・総会
    • Place of Presentation
      岐阜
    • Related Report
      2011 Final Research Report
  • [Presentation] 実験的矯正移動にともなうアクアポリン1陽性細胞の観察2011

    • Author(s)
      Anwar Humayra Binte, 河野芳朗, 木下-河野承子, 野澤-井上佳世子, 斎藤功, 前田健康
    • Organizer
      第53回歯科基礎医学会
    • Place of Presentation
      岐阜市長良川国際会議場(招待講演)
    • Related Report
      2011 Annual Research Report
  • [Presentation] アルキル化抗腫瘍薬によるラット歯根形成障害に関する組織形態学的解析2010

    • Author(s)
      三富智恵
    • Organizer
      第52回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Related Report
      2011 Final Research Report
  • [Presentation] 実験的咬合性外傷における歯周組織破壊・改変に伴うアクアポリン1発現の変化2010

    • Author(s)
      河野承子
    • Organizer
      第52回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Related Report
      2011 Final Research Report
  • [Presentation] 実験的外傷歯の歯周組織におけるAQP1陽性細胞の動態2010

    • Author(s)
      河野承子
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Final Research Report
  • [Presentation] 抗腫瘍薬がラット臼歯歯根形成におよぼす影響2010

    • Author(s)
      三富智恵
    • Organizer
      第48回日本小児歯科学会大会
    • Place of Presentation
      名古屋
    • Related Report
      2011 Final Research Report
  • [Presentation] ラット切歯におけるセメント芽細胞の運命2010

    • Author(s)
      河野芳朗
    • Organizer
      第115回日本解剖学会総会・全国学術大会
    • Place of Presentation
      岩手
    • Related Report
      2011 Final Research Report
  • [Presentation] 実験的咬合性外傷における歯周組織破壊・改変に伴うアクアポリン1発現の変化2010

    • Author(s)
      河野承子, 河野芳朗, 他
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] アルキル化抗腫瘍薬によるラット歯根形成障害に関する組織形態学的解析2010

    • Author(s)
      三富智恵, 河野芳朗, 他
    • Organizer
      第52回歯科基礎医学会学術大会
    • Place of Presentation
      東京
    • Related Report
      2010 Annual Research Report
  • [Presentation] Col3.6-Dlx5 expression promotes odontoblast differentiation and affects Dlx5, Dlx3, and Dspp expression2010

    • Author(s)
      Veana-Lea Ferrer, Yoshiro kawano, et al
    • Organizer
      AADR/CADR Annual Meeting 2010 Washington, DC
    • Place of Presentation
      ワシントンDC
    • Related Report
      2009 Annual Research Report
  • [Presentation] ラット切歯におけるセメント芽細胞の運命2010

    • Author(s)
      河野芳朗, 他
    • Organizer
      第115回日本解剖学会総会・全国学術大会
    • Place of Presentation
      盛岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] 歯胚中間層における67kD laminin receptor(67LR)の発現:星状網における血管網形成との相関2009

    • Author(s)
      河野芳朗
    • Organizer
      第51回歯科基礎医学会学術大会・総会
    • Place of Presentation
      新潟
    • Related Report
      2011 Final Research Report
  • [Presentation] 歯槽骨の発生におけるアクアポリン1(AQP1)陽性細胞の出現2009

    • Author(s)
      河野芳朗
    • Organizer
      第114回日本解剖学会総会・全国学術大会
    • Place of Presentation
      岡山
    • Related Report
      2011 Final Research Report
  • [Presentation] 歯胚中間層における67kD laminin receptor(67LR)の発現:星状綱における血管綱形成との相関2009

    • Author(s)
      河野芳朗, 他
    • Organizer
      第51回歯科基礎医学会学術大会
    • Place of Presentation
      新潟
    • Related Report
      2009 Annual Research Report
  • [Book] II編7章4.特殊感覚器の構造と機能.最新歯科衛生士教本人体の構造と機能1解剖学・組織発生学・生理学2010

    • Author(s)
      河野芳朗,前田健康,山田小枝子
    • Publisher
      医歯薬出版
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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