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Relationships between feeding-related cognitive function and activity of reward system

Research Project

Project/Area Number 21592354
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Functional basic dentistry
Research InstitutionNiigata University

Principal Investigator

YAMAMURA Kensuke  新潟大学, 医歯学系, 教授 (90272822)

Co-Investigator(Kenkyū-buntansha) YAMADA Yoshiaki  新潟大学, 企画戦略本部, 教授 (80115089)
KITAGAWA Jyunichi  新潟大学, 医歯学系, 准教授 (50373006)
KUROSE Masayuki  新潟大学, 医歯学系, 助教 (40397162)
Co-Investigator(Renkei-kenkyūsha) NARITA Noriyuki  日本大学, 歯学部, 准教授 (10155997)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
Keywords感覚 / 摂食行動 / 脳内報酬系 / 認知 / 嚥下
Research Abstract

The present study was conducted to clarify the role of sensory information related to feeding behavior on the cognition of palatability as well as crucial cortical area for such a cognitive function. Also, effects of cognition of palatability on feeding behaviors were also studied. Activity of various cortical areas was recorded in the healthy subjects using near infrared spectroscopy(NIRS), when the subjects performed various feeding-related tasks. The results revealed that the right dorsal prefrontal cortex plays a crucial role for the detection of various feeding-related sensory inputs, and its activity may be increased when the subjects recognize favorable tastes. Also using umami taste as a food additive with salty taste may serve not only as a flavor enhancer but also as an enhancer of swallow initiation.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (52 results)

All 2012 2011 2010 2009

All Journal Article (21 results) (of which Peer Reviewed: 21 results) Presentation (29 results) Patent(Industrial Property Rights) (2 results)

  • [Journal Article] Induction of the Swallowing Reflex by Electrical Stimulation of the Posterior Oropharyngeal Region in Awake Humans2012

    • Author(s)
      Takatsuji H, Zakir HM, Mostafeezur RM, Saito I, Yamada Y, Yamamura K, Kitagawa J
    • Journal Title

      Dysphagia

      Volume: (in press)

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The Digastric Muscle is Less Involved in Pharyngeal Swallowing in Rabbits2011

    • Author(s)
      Tsujimura T, Yamada A, Nakamura Y, Fukuhara T, Yamamura K, Inoue M
    • Journal Title

      Dysphagia

      Volume: 27(2) Pages: 271-6

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of electrical stimulation of the superior laryngeal nerve on the jaw-opening reflex2011

    • Author(s)
      Fukuhara T, Tsujimura T, Kajii Y, Yamamura K, Inoue M
    • Journal Title

      Brain Res

      Volume: 1391 Pages: 44-53

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Effects of electrical stimulation of the superior laryngeal nerve on the jaw-opening reflex2011

    • Author(s)
      Fukuhara T
    • Journal Title

      Brain Res

      Volume: in press

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of spindle discharge from jaw-closing muscles during chewing foods of different hardness in awake rabbits2010

    • Author(s)
      Zakir HM, Kitagawa J, Yamada Y, Kurose M, Mostafeezur RM, Yamamura K.
    • Journal Title

      Brain Res Bull

      Volume: 83(6) Pages: 380-386

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural mechanisms of swallowing and effects of taste and other stimulation on swallow initiation2010

    • Author(s)
      Yamamura K., Kitagawa J., Kurose M., Sugino S., Takatsuji H., Rahman M., Hossain Z., Yamada Y
    • Journal Title

      Biol. Pharm. Bull

      Volume: 33(11) Pages: 1786-1790

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Neural mechanisms of swallowing and effects of taste and other stimuli on swallow initiation.2010

    • Author(s)
      Yamamura K
    • Journal Title

      Biol Pharm Bull

      Volume: 33 Pages: 1786-1790

    • NAID

      130000402296

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Modulation of spindle discharge from jaw-closing muscles during chewing foods of different hardness in awake rabbits.2010

    • Author(s)
      Zakir HM
    • Journal Title

      Brain Res Bull

      Volume: 83 Pages: 380-386

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 嚥下誘発と味覚・うま味の関連2010

    • Author(s)
      山田好秋
    • Journal Title

      日本味と匂学会誌

      Volume: 17 Pages: 127-132

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chewing-related prefrontal cortex activation while wearing partial denture prothesis2009

    • Author(s)
      Narita, N., Kamiya, K., Yamamura, K., Kawasaki, S., Matsumoto, T., Tanaka, N.
    • Journal Title

      J. Prosthodontic Res

      Volume: 53 Pages: 126-135

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Mastication-induced modulation of the jaw-opening reflex during different periods of mastication in awake rabbits2009

    • Author(s)
      Rahman M, Yamamura K, Kurose M, Yamada Y
    • Journal Title

      Brain Research

      Volume: 1254 Pages: 28-37

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Taste and Health : New Frontiers in Oral Physiology and Rehabilitation Foreword2009

    • Author(s)
      Yamada Y
    • Journal Title

      JOURNAL OF HEALTH SCIENCE 55

      Pages: 663-663

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Physiological Significance of Taste on Ingestion and Swallowing2009

    • Author(s)
      Yamada Y
    • Journal Title

      JOURNAL OF HEALTH SCIENCE 55

      Pages: 664-666

    • NAID

      130000127951

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chewing-related prefrontal cortex activation while wearing partial denture prothesis2009

    • Author(s)
      Narita N
    • Journal Title

      JOURNAL OF Prosthodontic Research 53

      Pages: 126-153

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Possible Applications of Umami Taste to Improve Eating Disorders2009

    • Author(s)
      Uneyama H
    • Journal Title

      JOURNAL OF HEALTH SCIENCE 55

      Pages: 699-700

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Activity pattern of swallowing-related muscles、food properties and bodyposition in normal humans2009

    • Author(s)
      Inagaki D
    • Journal Title

      JOURNAL OF ORAL REHABILITATION 36

      Pages: 703-709

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Effects of food texture and head posture on oropharyngeal swallowing2009

    • Author(s)
      Tsukada T
    • Journal Title

      JOURNAL OF APPLIED PHYSIOLOGY 106

      Pages: 1848-1857

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Mastication-induced modulation of the jaw-opening reflex during different periods of mastication in awake rabbits2009

    • Author(s)
      Mostafeezur RM
    • Journal Title

      BRAIN RESEARCH 1254

      Pages: 28-37

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Influence of food properties and body position on swallowing-related muscle activity amplitude2009

    • Author(s)
      Inagaki D
    • Journal Title

      JOURNAL OF ORAL REHABILITATION 36

      Pages: 176-183

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Constancy of Head Turning Recorded in Healthy Young Humans2009

    • Author(s)
      Miyaoka S
    • Journal Title

      ANNALS OF BIOMEDICAL ENGINEERING 37

      Pages: 428-436

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 食と健康をめぐる諸問題:歯学の観点から2009

    • Author(s)
      山村健介
    • Journal Title

      新潟医学会雑誌別冊 123

      Pages: 281-284

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 味刺激が嚥下誘発に及ぼす影響2012

    • Author(s)
      山村健介
    • Organizer
      日本薬学会第132年会味の素(株)スポンサードシンポジウム
    • Place of Presentation
      札幌、北海道大学
    • Year and Date
      2012-03-30
    • Related Report
      2011 Annual Research Report
  • [Presentation] ヒト嚥下誘発におけるうま味刺激の影響2011

    • Author(s)
      内田喜昭、山村健介
    • Organizer
      日本味と匂学会第45回大会
    • Place of Presentation
      金沢、石川県立音楽堂
    • Year and Date
      2011-10-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 脳科学から見た口腔機能-口腔からの食物摂取の重要性2011

    • Author(s)
      山村健介.
    • Organizer
      第24回日本口腔診断学会教育講演
    • Place of Presentation
      東京
    • Year and Date
      2011-05-22
    • Related Report
      2011 Final Research Report
  • [Presentation] 脳科学から見た口腔機能-口腔からの食物摂取の重要性2011

    • Author(s)
      山村健介
    • Organizer
      第24回日本口腔診断学会
    • Place of Presentation
      東京、東京医科歯科大学(招待講演)
    • Year and Date
      2011-05-22
    • Related Report
      2011 Annual Research Report
  • [Presentation] Recent insights into swallowing initiation2010

    • Author(s)
      Yamamura K
    • Organizer
      International joint symposium on oral science
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2010-12-17
    • Related Report
      2011 Final Research Report
  • [Presentation] Recent insights into swallowing initiation.2010

    • Author(s)
      Yamamura K
    • Organizer
      International joint symposium on oral science
    • Place of Presentation
      Bali, Indonesia
    • Year and Date
      2010-12-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 表情筋トレーニングの定量的効果測定2010

    • Author(s)
      長津聡子、朝日藤寿一、山田好秋、齋藤功、山村健介
    • Organizer
      平成22年度新潟歯学会第2回例会
    • Place of Presentation
      新潟
    • Year and Date
      2010-11-13
    • Related Report
      2011 Final Research Report
  • [Presentation] 咀嚼と脳2010

    • Author(s)
      山村健介
    • Organizer
      平成22年度新潟歯学会第1回例会
    • Place of Presentation
      新潟
    • Year and Date
      2010-07-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 咀囑と脳2010

    • Author(s)
      山村健介
    • Organizer
      平成22年度新潟歯学会 第一回例会
    • Place of Presentation
      新潟
    • Year and Date
      2010-07-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] 嚥下誘発と味覚・うま味の関連2010

    • Author(s)
      山田好秋
    • Organizer
      うま味研究会公開シンポジウム
    • Place of Presentation
      東京
    • Year and Date
      2010-05-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 味覚による咀嚼・嚥下調節2010

    • Author(s)
      山村健介
    • Organizer
      日本薬学会第130年会シンポジウム
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 味覚による咀囑・嚥下調節2010

    • Author(s)
      山村健介
    • Organizer
      第130回日本薬学会年会
    • Place of Presentation
      岡山
    • Year and Date
      2010-03-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] ヒト咽頭領域への電気および味覚同時刺激による嚥下誘発効果2010

    • Author(s)
      高辻華子
    • Organizer
      第4回三叉神経感覚-運動統合機能研究会
    • Place of Presentation
      大阪
    • Related Report
      2011 Final Research Report
  • [Presentation] ヒト咽頭領域への電気および味覚同時刺激による嚥下誘発効果2010

    • Author(s)
      高辻華子、北川純一、杉野伸一郎、井表千馨、杉山尚道、ジャキール・モハマド・ホッサイン、モスターフィーズ・ラーマン、山田好秋、齋藤功、山村健介
    • Organizer
      第69回日本矯正歯科学会大会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] ヒト咽頭領域への化学刺激が嚥下誘発に及ぼす影響2010

    • Author(s)
      高辻華子、北川純一、Zakir Hossain、Mostafeezur Rahman、杉野伸一郎、山田好秋、齋藤功、山村健介
    • Organizer
      第52回歯科基礎医学会学術大会・総会
    • Place of Presentation
      東京
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] 咀嚼と脳2009

    • Author(s)
      山村健介
    • Organizer
      特定非営利活動法人日本咀嚼学会第15回咀嚼と健康ファミリーフォーラム
    • Place of Presentation
      福岡
    • Year and Date
      2009-10-04
    • Related Report
      2011 Final Research Report
  • [Presentation] 味覚生理研究のフロンティアオーバービュー2009

    • Author(s)
      山田好秋
    • Organizer
      第51回歯科基礎医学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-09-11
    • Related Report
      2009 Annual Research Report
  • [Presentation] 介護老人福祉施設の組織構造の実態と介護職員の評価2009

    • Author(s)
      鈴木温子
    • Organizer
      第42回新潟歯学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 継続的な口腔保健指導による味覚閾値の変化2009

    • Author(s)
      高野弘子
    • Organizer
      第42回新潟歯学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 全国の通信制高等学校における保健室の実態と課題2009

    • Author(s)
      増田明美
    • Organizer
      第42回新潟歯学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 下顎運動時における頭頸部協調運動2009

    • Author(s)
      敦井智賀子
    • Organizer
      第42回新潟歯学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] 口腔体操と障害者の口腔状況の変化2009

    • Author(s)
      松田みどり
    • Organizer
      第42回新潟歯学会
    • Place of Presentation
      新潟
    • Year and Date
      2009-04-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] SPINDLE AFFERENTS DISCHARGE OF JAW-CLOSING MUSCLES DURLNG CHEWING DIFFERENT HARDNESS OF FOODS IN AWAKE RABBITS2009

    • Author(s)
      Hossain Z
    • Organizer
      36th International congress of physiological sciences
    • Place of Presentation
      Kyoto、Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] DEVELOPMENT OF A SYSTEM TO ELICIT SAWLLOWING BY ELECTRICAL STIMULATION IN MAN2009

    • Author(s)
      Kurose M
    • Organizer
      36th International congress of physiological sciences
    • Place of Presentation
      Kyoto、Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] ANALYSIS THE CHARACTERISTIC OF ORAL DEHAVIORS BY THE THREE DIMENSIONAL JAW-TRACKING SYSTEM IN FREELY MOVING RATS2009

    • Author(s)
      Rahman M
    • Organizer
      36th International congress of physiological sciences
    • Place of Presentation
      Kyoto、Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] EFFECTS OF ELECTRICAL STIMULATION IN THE PHARYNGEAL REGION ON THE REFLEX SWALLOWING2009

    • Author(s)
      Adachi T
    • Organizer
      36th International congress of physiological sciences
    • Place of Presentation
      Kyoto、Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] CHANGE IN THE THRESHOLD OF REFLEXIVELY-EVOKED SWALLOWING DURING SLEEPIN MAN2009

    • Author(s)
      Yamamura K
    • Organizer
      36th International congress of physiological sciences
    • Place of Presentation
      Kyoto、Japan
    • Related Report
      2009 Annual Research Report
  • [Presentation] 電気刺激を用いた嚥下誘発システムの開発2009

    • Author(s)
      杉野伸一郎
    • Organizer
      日本矯正歯科学会第68回大会
    • Place of Presentation
      褊岡
    • Related Report
      2009 Annual Research Report
  • [Presentation] 摂食機能を理解するための基礎知識2009

    • Author(s)
      山田好秋
    • Organizer
      中国栄養老年分会
    • Place of Presentation
      中国、上海
    • Related Report
      2009 Annual Research Report
  • [Patent(Industrial Property Rights)] 嚥下誘発装置2011

    • Inventor(s)
      山田好秋、山村健介他
    • Industrial Property Rights Holder
      新潟大学
    • Industrial Property Number
      2011-070811
    • Filing Date
      2011-03-28
    • Related Report
      2011 Final Research Report
  • [Patent(Industrial Property Rights)] 嚥下誘発装置2011

    • Inventor(s)
      山田好秋, ほか3名
    • Industrial Property Rights Holder
      新潟大学
    • Filing Date
      2011-03-28
    • Related Report
      2010 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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