Analysis of the salivatin function as incretin mimetics
| Project/Area Number |
21592363
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional basic dentistry
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| Research Institution | The University of Tokushima |
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Principal Investigator |
MIZUSAWA Noriko 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (80254746)
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| Co-Investigator(Kenkyū-buntansha) |
IWATA Takeo 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (10350399)
YOSHIMOTO Katsuhiko 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 教授 (90201863)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | 糖尿病 / 膵島 / 唾液 / インクレチン / インスリン |
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| Research Abstract |
Incretin mimetics are a new class of pharmacological agents with multiple antihyperglycemic actions that mimic several of the actions of incretin hormones originating in the gut, such as glucagon-like peptide (GLP)-1.Salivatin supplied from salivary gland is a candidate to be new incretin mimetics. But the significant anti-hyperglycemic actions were unclear.
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Report
(4 results)
Research Products
(25 results)
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[Presentation] Down-regulated expression of p18INK4C in pituitary adenomas2010
Author(s)
Katsuhiko Yoshimoto, Md. Golam Hossain, Takeo Iwata, Noriko Mizusawa, Schadan Wan Nazatul Shima, Toru Okutsu, Kyoko Ishimoto, Zhi Rong Qian, Toshiaki Sano, Shozo Yamada
Organizer
14^<th> International Congress of Endocrinology
Place of Presentation
Kyoto. Kyoto International Conference Center
Related Report
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