| Project/Area Number |
21592370
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Functional basic dentistry
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| Research Institution | Health Sciences University of Hokkaido |
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Principal Investigator |
IZUMI Hiroshi 北海道医療大学, 歯学部, 教授 (20108541)
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| Co-Investigator(Kenkyū-buntansha) |
ISHII Hisayoshi 北海道医療大学, 歯学部, 講師 (00275489)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,510,000 (Direct Cost: ¥2,700,000、Indirect Cost: ¥810,000)
Fiscal Year 2011: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
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| Keywords | 交感神経 / 血管拡張 / アドレナリン / アドレナリンβ受容体 / 副腎髄質 / 咀嚼筋 / カテコラミン / アドレナリン受容体 / 内臓神経 / 交感神経節前線維 / ラット / レーザードップラー血流計 |
|---|
| Research Abstract |
The present study was designed to examine the effects of circulating catecholamines released by sympathoadrenal system on the haemodynamics of the masseter muscle. The results of the present study indicate that circulating adrenaline elicits acute vasodilatation through aβ-adrenergic mechanism in the rat masseter muscle. Vascularβ_2-adrenergic receptors in the masseter muscle may be activated preferentially by adrenaline released from the adrenal medulla, suggesting that the sympathoadrenal system is involved in the marked jaw muscle blood flow increase during sympathoexcitation.
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