| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
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| Research Abstract |
This study evaluated the potential usefulness of[^<18> F] Choline as a new cancer tracer for PET. The uptake of[^<18> F] Choline and[^<18> F] FDG are cell cycle dependent, are associated with the proliferative activity of the tumor seen during PET imaging. The average SUVs of[^<18> F] FDG for the gingival cancer infiltrated jawbone was markedly higher than that for the tongue. The average SUVs of[^<11> C] or[^<18> F] Choline were showing no significant difference between the tongue and gingival cancer, and the same level as[^<18> F] FDG uptake for the tongue cancer. It seems that[^<18> F] Choline is not well incorporated to the osteogenetic cell and the osteoclast related to bone metabolism but accumulation for the cancer cells.
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