The analysis of function and localization of matrixmetalloproteinase in the process of forming tertiary dentin.
| Project/Area Number |
21592419
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
ITOH Shousaku 大阪大学, 大学院・歯学研究科, 助教 (90360495)
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| Co-Investigator(Kenkyū-buntansha) |
YABUNE Toshiaki 大阪大学, 大学院・歯学研究科, 助教 (90423144)
ABE Makoto 大阪大学, 大学院・歯学研究科, 助教 (40448105)
TAKAHASI Yusuke 大阪大学, 大学院・歯学研究科, 助教 (60397693)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
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| Keywords | 修復象牙質 / MMPファミリー / in situ hydridization / MDPC-23 / 窩洞形成 / in situ hybridization / 骨芽細胞 / 石灰化 / 覆髄剤 / 硬組織産生細胞 / カルシウムセンシングレセプター / シグナル |
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| Research Abstract |
TIMP1, which promotes the mineralization of odontoblast and activates undifferentiated mesenchymal cells via Wnt/β-catenin pathway in the pulp after cavity preparation, might be one of a critical molecule for tertiary dentinogenesis and one of a candidate for a new" biological" pulp capping materials.
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Report
(4 results)
Research Products
(10 results)
