Study on regeneration of dentin-enamel complex by the bone marrow mesenchymal stem cells
| Project/Area Number |
21592420
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Conservative dentistry
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| Research Institution | Okayama University |
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Principal Investigator |
IZAWA Shunji 岡山大学, 大学院・医歯薬学総合研究科, 助教 (20273998)
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| Co-Investigator(Renkei-kenkyūsha) |
YOSHIYAMA Masahiro 岡山大学, 大学院・医歯薬学総合研究科, 教授 (10201071)
NISHITANI Yoshihiro 岡山大学, 大学院・医歯薬学総合研究科, 准教授 (60325123)
YAMAJI Kozo 岡山大学, 岡山大学病院, 講師 (30374531)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥520,000 (Direct Cost: ¥400,000、Indirect Cost: ¥120,000)
Fiscal Year 2009: ¥3,770,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥870,000)
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| Keywords | 保存修復学 / ヒト骨髄間葉系幹細胞 / TNFα / ファクトリー仮説 / 全能性賦活因子 / 象牙質・エナメル質複合体の生成 / 組織環境 / エムドゲングル / ペプチドハイドロゲル / 象牙芽細胞分化 / 象牙質再生 |
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| Research Abstract |
Every cell can differentiate into target cell and regenerate target tissue via embryo-stem cell under the condition that RNA polymeraseIIthat takes on first step transcription of gene expression, change from free state to systematized state by TNFαwhich is typical inflammatory cytokine and appropriate activation factor and organizational environment factor(scaffold, differentiation factor, culture media).
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Report
(4 results)
Research Products
(8 results)
