| Project/Area Number |
21592497
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Dental engineering/Regenerative dentistry
|
|---|
| Research Institution | The University of Tokushima |
|---|
Principal Investigator |
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NAGAO Daisuke 徳島大学, 大学院・ヘルスバイオサイエンス研究部, 助教 (90432749)
NAITOU Yoshihito 徳島大学, 病院, 助教 (20509773)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
|
|---|
| Keywords | 歯学 / インプラント補綴 / 放射線障害 / 骨芽細胞様細胞 / 持続的圧縮力 |
|---|
| Research Abstract |
The aim of this study was to estimate the response of the irradiated tissue added the compressing force. Mouse osteoblast-like cells were compressed directly after the irradiation, gene expression of apoptosis channel was examined. Activation of caspase significant increased with stronger radiation, and decreased with the compressed force. It was recognized that gene expression related to prevention of apoptosis were increased under the compressing force.
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