| Project/Area Number |
21592498
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Dental engineering/Regenerative dentistry
|
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| Research Institution | Kyushu University |
|---|
Principal Investigator |
TSURU Kanji 九州大学, 歯学研究院, 准教授 (50314654)
|
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| Co-Investigator(Renkei-kenkyūsha) |
ISHIKAWA Kunio 九州大学, 歯学研究院, 教授 (90202952)
|
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| Project Period (FY) |
2009 – 2012
|
| Project Status |
Completed (Fiscal Year 2012)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
|
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| Keywords | インターフェイス / 有機-無機 / 炭酸アパタイト / 生体材料 / 有機－無機 |
|---|
| Research Abstract |
Carbonate apatite (CO_3Ap) foam which mimics the structure and inorganic composition of teeth and bone is expected for medical use as a bone substitute which can be replaced to new bone. However a mechanical strength improvement of CO3Ap is necessary. In this study, therefore, the mechanical strength improvement of CO_3 Ap was examined by regulating interface between organic and inorganic substances. Addition of 5wt% polyvinyl alcohol to precursor slurry enhanced interaction between precursor powders and polyurethane template and it affected to increase the compressive strength of obtained CO_3Ap foam. Besides, reinforcement of CO_3Ap foam was successfully achieved by coating with polylactic acid containing appropriate amount of CO3Ap granules without changing its morphology and composition.
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