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Mechanical strength improvement of carbonate apatite foam by regulatingorganic-inorganic interface

Research Project

Project/Area Number 21592498
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionKyushu University

Principal Investigator

TSURU Kanji  九州大学, 歯学研究院, 准教授 (50314654)

Co-Investigator(Renkei-kenkyūsha) ISHIKAWA Kunio  九州大学, 歯学研究院, 教授 (90202952)
Project Period (FY) 2009 – 2012
Project Status Completed (Fiscal Year 2012)
Budget Amount *help
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Keywordsインターフェイス / 有機-無機 / 炭酸アパタイト / 生体材料 / 有機-無機
Research Abstract

Carbonate apatite (CO_3Ap) foam which mimics the structure and inorganic composition of teeth and bone is expected for medical use as a bone substitute which can be replaced to new bone. However a mechanical strength improvement of CO3Ap is necessary. In this study, therefore, the mechanical strength improvement of CO_3 Ap was examined by regulating interface between organic and inorganic substances. Addition of 5wt% polyvinyl alcohol to precursor slurry enhanced interaction between precursor powders and polyurethane template and it affected to increase the compressive strength of obtained CO_3Ap foam. Besides, reinforcement of CO_3Ap foam was successfully achieved by coating with polylactic acid containing appropriate amount of CO3Ap granules without changing its morphology and composition.

Report

(4 results)
  • 2012 Final Research Report ( PDF )
  • 2011 Annual Research Report
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2012 2011 2010

All Journal Article (2 results) (of which Peer Reviewed: 1 results) Presentation (2 results)

  • [Journal Article] Reinforcement of carbonate apatite bone substitutes with carbonate apatite by Ca salt introduction2010

    • Author(s)
      Kanako Matsumoto, Kanji Tsuru, Giichiro Kawachi, Michito Maruta, Shigeki Matsuya, Ichiro Takahashi, Kunio Ishikawa
    • Journal Title

      Journal of the Ceramics Society of Japan

      Volume: 118(6) Pages: 521-524

    • NAID

      130000304781

    • Related Report
      2012 Final Research Report
  • [Journal Article] Reinforcement of Carbonate Apatite Bone Substitutes with Carbonate Apatite by Ca Salt Introduction2010

    • Author(s)
      Kanako Matsumoto, Kanji Tsuru, Giichiro Kawachi, Michito Maruta, Shigeki Matsuya, Ichiro Takahashi, Kunio Ishikawa
    • Journal Title

      Journal of the Ceramics Society of Japan

      Volume: 118 Pages: 521-524

    • NAID

      130000304781

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] Reinforcement of carbonate apatite foam by coating with poly-L-lactic acidcontaining carbonate apatite granules2012

    • Author(s)
      Kanji Tsuru, Girlie M. Munar, Melvin L. Munar, Michito Maruta, Shigeki Matsuya, Kunio Ishikawa
    • Organizer
      9th World Biomaterials Congress
    • Place of Presentation
      Chengdu, China
    • Related Report
      2012 Final Research Report
  • [Presentation] Calcite Bone Substitute Prepared from Calcium Hydroxide Compact Using Heat-treatment under Carbon Dioxide Atmosphere2011

    • Author(s)
      Kanji Tsuru, Akihiro Otsu, Michito Maruta, Alireza Valanezhad, Giichiro Kawachi, Akari Takeuchi, Shigeki Matsuya, Kunio Ishikawa
    • Organizer
      The 23rd Symposium and Annual Meeting of International Society for Ceramics in Medicine (Bioceramics 23)
    • Place of Presentation
      Istanbul, Turkey
    • Related Report
      2012 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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