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Development of ribbon-like OCP/apatite mixed crystals and collagen composite with toughness

Research Project

Project/Area Number 21592505
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Dental engineering/Regenerative dentistry
Research InstitutionAsahi University

Principal Investigator

IIJIMA Mayumi  朝日大学, 歯学部, 助教 (80164838)

Co-Investigator(Kenkyū-buntansha) WAKAMATSU Nobukazu  朝日大学, 歯学部, 講師 (00158594)
KAMEMIZU Hideo  朝日大学, 歯学部, 講師 (00152877)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2009: ¥3,380,000 (Direct Cost: ¥2,600,000、Indirect Cost: ¥780,000)
Keywords生体材料 / コラーゲン / オクタカルシウムリン酸塩 / アパタイト / 曲げ強さ / 靭性 / Young率 / 複合材料・物性 / 曲げ挙動
Research Abstract

We have been developing an osteoconductive composite with both strength and toughness, using octacalcium phosphate(OCP)/apatite crystal and type I collagen. Composite was consolidated at room temperature or 40℃under dry and wet conditions. Mechanical property of the consolidated blocks was measured by 3-point bending tests. It was found that the consolidation temperature and wetness were critical to increase the strength and toughness. While, Youngs' modulus was increased by dry consolidation at 40℃.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (11 results)

All 2012 2011 2010 2009 Other

All Journal Article (1 results) Presentation (10 results)

  • [Journal Article] Relationship between composition, structure and flexural behavior of OCP/apatite-type I collagen composite2009

    • Author(s)
      M.Iijima, N.Wakamatu, H.Kamemizu, M.Adachi, Y.Doi
    • Journal Title

      Arch BioCeramics Res 9

      Pages: 339-342

    • NAID

      130006961753

    • Related Report
      2009 Annual Research Report
  • [Presentation] オクタカルシウムリン酸塩/アパタイト複合結晶とコラーゲン複合体の成形条件と曲げ挙動2012

    • Author(s)
      飯島まゆみ, 若松宣一、亀水秀男, 他
    • Organizer
      第59回日本歯科理工学会学術講演会
    • Place of Presentation
      徳島県郷土文化会館
    • Year and Date
      2012-04-15
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] Flexural behavior of octacalcium phosphate(OCP)/apatite-type I collagen composite consolidated by warm isostatic pressing2012

    • Author(s)
      M. Iijima, N. Wakamatu, H. Kamemizu, et al
    • Organizer
      12^<th>-International Symposium on Biomimetic Materials Processing
    • Place of Presentation
      Nagoya University
    • Year and Date
      2012-01-25
    • Related Report
      2011 Final Research Report
  • [Presentation] Flexural behavior of octacalcium phosphate (OCP)/apatite-type I collagen composite consolidated by warm isostatic pressing2012

    • Author(s)
      M.Iijima, N.Wakamatu, H.Kamemizu, M.Adachi, Y.Doi
    • Organizer
      12^<th>-International Symposium on Biomimetic Materials Processing
    • Place of Presentation
      Nagoya University
    • Year and Date
      2012-01-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] オクタカルシウムリン酸塩/アパタイト複合結晶とコラーゲン複合体の曲げ挙動-温水等方圧プレスの効果2011

    • Author(s)
      飯島まゆみ、若松宣一、亀水秀男、足立正徳、土井豊
    • Organizer
      第58回日本歯科理工学会学術講演会
    • Place of Presentation
      奥羽大学(福島県)
    • Year and Date
      2011-10-23
    • Related Report
      2011 Annual Research Report
  • [Presentation] Flexural Behavior of Collagenous Matrix Consolidated by a Warm Isostatic Pressing2011

    • Author(s)
      M. Iijima, N. Wakamatu, H. Kamemizu, et al
    • Organizer
      International Dental Materials Congress 2011
    • Place of Presentation
      Seoul, Korea
    • Related Report
      2011 Annual Research Report 2011 Final Research Report
  • [Presentation] オクタカルシウムリン酸塩(OCP)/アパタイト複合結晶コラーゲン複合体の曲げ挙動:湿潤成形の効果について2010

    • Author(s)
      飯島まゆみ, 若松宣一、亀水秀男, 他
    • Organizer
      第55回日本歯科理工学会学術講演会
    • Place of Presentation
      船堀コンベンションセンター(千葉県)
    • Year and Date
      2010-04-17
    • Related Report
      2011 Final Research Report 2010 Annual Research Report
  • [Presentation] オクタカルシウムリン酸塩(OCP)/アパタイト複合結晶存在下でのコラーゲンの再線維化2009

    • Author(s)
      M.Iijima, N.Wakamatu, H.Kamemizu, M.Adachi, Y.Doi
    • Organizer
      Biomineralization Workshop
    • Place of Presentation
      東京大学・弥生講堂
    • Year and Date
      2009-12-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] Relationship between composition, structure and flexural behavior of OCP/apatite-type I collagen composite2009

    • Author(s)
      M.Iijima, N.Wakamatu, H.Kamemizu, M.Adachi, Y.Doi
    • Organizer
      9^<th> Asian BioCeramics Symposium
    • Place of Presentation
      Nagoya Congress Center
    • Year and Date
      2009-12-10
    • Related Report
      2009 Annual Research Report
  • [Presentation] アスペクト比の大きなオクタカルシウムリン酸塩(OCP)/アパタイト複合結晶存在下におけるアテロコラーゲンの再線維化2009

    • Author(s)
      M.Iijima, N.Wakamatu, H.Kamemizu, M.Adachi, Y.Doi
    • Organizer
      日本結晶成長学会
    • Place of Presentation
      名古屋大学・豊田講堂
    • Year and Date
      2009-10-13
    • Related Report
      2009 Annual Research Report
  • [Presentation] オクタカルシウムリン酸塩/アパタイト複合結晶とコラーゲン複合体の曲げ挙動-温水等方圧プレスの効果

    • Author(s)
      飯島まゆみ、若松宣一、亀水秀男, 他
    • Organizer
      第58回日本歯科理工学会学術講演会
    • Place of Presentation
      奥羽大学
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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