| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
In a common strategy of bone tissue engineering, stem cells are differentiated into osteoblastic cells using differentiation-inducing agents. This study showed that human dental pulp cells cultured without osteogenic differentiation induction possessed the capacity to generate bone tissues in vivo. Furthermore, human dental pulp cells expanded in serum-free condition formed bone-like tissues in vivo. These results lead to set up a simple and safety strategy of bone tissue engineering like not previous.
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