Development of diagnostic panel of oral cancer cell properties by genetic polymorphisms and expression properties
| Project/Area Number |
21592543
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Tsurumi University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
KAMIYA Yoko 鶴見大学, 歯学部, 非常勤講師 (10460213)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,210,000 (Direct Cost: ¥1,700,000、Indirect Cost: ¥510,000)
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| Keywords | 遺伝子発現 / 遺伝子多型 / 癌細胞特性 / 口腔扁平上皮癌 / バイオインフォマティクス / バイオイテンフォマティクス |
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| Research Abstract |
In order to understand the relationship between OSCC properties and gene mutation and to establish a standard for selection of therapy, the variety of gene expression and polymorphism and individual OSCC cell properties was analyzed. This study was conducted with the approval of Tsurumi University ethical review board. Informed consent was obtained from all of patients prior to this study.
We performed SNP analysis to determine the gene polymorphism, DNA microarray analysis and proteome analysis. The common candidate in all analysis was not found but there is potential in combinations of plural candidates.
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Report
(4 results)
Research Products
(2 results)
