| Project/Area Number |
21592550
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MORI Shiro 東北大学, 病院, 講師 (80230069)
KODAMA Tetsuya 東北大学, 大学院・医工学研究科, 教授 (40271986)
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| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 口腔癌 / ナノバブル / 超音波 / 術中迅速診断 / リアルタイム |
|---|
| Research Abstract |
The aim of the present study is to develop a real time imaging diagnosis system for oral cancer using nanobubbles and high-frequency ultrasound. As a result, the following problems were revealed, halation caused by the ultrasound contrast agent, blurring of the image caused by arterial pulsation, and imaging of the immature angiogenesis of the tumor. On the other hand, the diagnostic accuracy could be improved by analyzing the four-dimentional dynamics of nanobubbles in the blood flow. In this stu dy, to solve the problems, hardware and software of the high frequency-ultrasound imaging system were improved
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