Exploitation of MICA gene polymorphism for development of personalized medicine in oral cancer patients
| Project/Area Number |
21592553
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Hiroshima University |
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Principal Investigator |
TANI Ryouji 広島大学, 病院, 助教 (10291486)
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| Co-Investigator(Kenkyū-buntansha) |
OKAMOTO Tetsuji 広島大学, 医歯薬学総合研究科, 教授 (00169153)
TORATANI Shigeaki 広島大学, 病院, 講師 (90172220)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2009: ¥2,470,000 (Direct Cost: ¥1,900,000、Indirect Cost: ¥570,000)
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| Keywords | MICA gene polymorphism / oral cancer / soluble MICA / personalized medicine / MICA / sMICA / NK細胞 / 口腔癌 / 蛋白分解酵素 |
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| Research Abstract |
The soluble MICA(_sMICA) in conditioned medium was measured by ELISA and we found the high level of_sMICA in KO cells. We have purified sMICA produced by KO cells.
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Report
(4 results)
Research Products
(11 results)
