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New approach to the mechanism of the pain by orthodontic tooth movement

Research Project

Project/Area Number 21592596
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Orthodontic/Pediatric dentistry
Research InstitutionOkayama University

Principal Investigator

MURAKAMI Takashi  岡山大学, 岡山大学病院, 助教 (00534786)

Co-Investigator(Kenkyū-buntansha) KAMIOKA Hiroshi  岡山大学, 大学院・医歯薬学総合研究科, 准教授 (80253219)
YAMASHIRO Takashi  岡山大学, 大学院・医歯薬学総合研究科, 教授 (70294428)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,820,000 (Direct Cost: ¥1,400,000、Indirect Cost: ¥420,000)
Keywordsグリア / 痛み / 歯の移動 / 共焦点顕微鏡 / 組織学的形態計測
Research Abstract

Orthodontic tooth movement evokes a pain. As for the past research to the mechanism of the pain, the focus has been placed on neural cells. This research newly focused on glial cells surrounding neurons, and searched how glial cells involved in the development of the pain by orthodontic tooth movement. This research revealed not only temporal distribution of activated glial cells but also the involvement of CGRP and VR1 in central nervous system during orthodontic tooth movement.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (4 results)

All 2011 2010 2009

All Journal Article (2 results) (of which Peer Reviewed: 2 results) Presentation (2 results)

  • [Journal Article] 実験的歯の移動におけるvanilloid receptor subtype1を発現する三叉神経節ニューロンの経時的変化2011

    • Author(s)
      足立理恵
    • Journal Title

      岡山歯学会雑誌

      Volume: 30巻 Pages: 1-11

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] 実験的歯の移動におけるvanilloid receptor subtypelを発根する三叉神経節ニューロンの経時的変化2011

    • Author(s)
      足立理恵
    • Journal Title

      岡山歯学会雑誌

      Volume: 30 Pages: 1-11

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Presentation] 実験的歯の移動時の三叉神経節におけるVR-1陽性神経線維の経時的変化2010

    • Author(s)
      足立理恵
    • Organizer
      日本矯正歯科学会大会
    • Place of Presentation
      パシフィコ横浜(神奈川県)
    • Year and Date
      2010-09-27
    • Related Report
      2011 Final Research Report
  • [Presentation] 実験的歯の移動におけるc-fosの発現とグリア細胞の動態との関連性について2009

    • Author(s)
      足立理絵
    • Organizer
      日本矯正歯科学会大会
    • Place of Presentation
      マリンメッセ福岡(福岡県)
    • Year and Date
      2009-11-17
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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