| Project/Area Number |
21592601
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Orthodontic/Pediatric dentistry
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| Research Institution | Nagasaki University |
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Principal Investigator |
HOSOYA Yumiko 長崎大学, 大学院・医歯薬学総合研究科, 准教授 (80112803)
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| Co-Investigator(Kenkyū-buntansha) |
MIYAZAKI Masashi 日本大学, 歯学部, 教授 (70239391)
INOUE Takashi 東京歯科大学, 歯学部, 教授 (20125008)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
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| Keywords | 小児歯科学 / フッ化ジアミンシリケート / 脱灰乳歯 / 細管封鎖 / 再石灰化 / 齲蝕進行抑制 / 審美性 / 脱灰乳歯象牙質 |
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| Research Abstract |
Objective : Silver diamine fluoride[ SDF : Ag(NH_3)_2F] has been used to arrest caries in Japan. SDF staines the teeth black due to silver precipitation. To overcome this drawback, ammonium hexafluorosilicate[ AHF :(NH_4)_2F_6] was applied and observed the changes on color and structures of demineralized enamel and dentin of primary teeth. Results : AHF treatment did not cause visible discoloration. Enamel prisms and dental tubules appeared by demineralization were covered with precipitates by AHF application. Spherical filled membranous structure was observed in the saliva soaking groups. The EDS analysis showed no effective influence with AHF application on enamel, however, significantly higher F% and Ca/ P ratio were detected on the AHF applied dentin surfaces without artificial saliva soaking. Conclusions : AHF treatment showed the virtue of being not to cause tooth-discoloration, however, additional study to evaluate the efficacy on arresting caries treatment by AHF.
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