| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Fiscal Year 2009: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
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| Research Abstract |
The FDF was taken in(or invade) a cell and raised oxidation membrane potential after reaching to mitochondria, and it was revealed that the FDF finally aggravated production of IL-8. The gingival crevicular fluid from periodontitis patients and normal subjects(for each 21) was isolated, and measured the anti-FDF antibody titer each. As a result, the antibody titer of periodontitis patients showed significantly higher than that of control group. Furthermore, 3 clinical parameters(Pocket depth, Clinical Attachment Level(CAL) and Bleeding on probing) are correlated with the anti-FDF antibody titer. These results suggest that the titer was associated with the condition of patients.
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