Pathological roles of tissue inhibitors of metalloproteinases in the tissues of drug-induced fibrous gingival over growth.
Project/Area Number |
21592622
|
Research Category |
Grant-in-Aid for Scientific Research (C)
|
Allocation Type | Single-year Grants |
Section | 一般 |
Research Field |
Periodontal dentistry
|
Research Institution | Niigata University |
Principal Investigator |
|
Co-Investigator(Kenkyū-buntansha) |
NAKASONE Naohiro 新潟大学, 医歯学総合病院, 医員 (20447634)
|
Co-Investigator(Renkei-kenkyūsha) |
MARUYAMA Satoshi 新潟大学, 医歯学総合病院, 講師 (30397161)
NOUNO Kaname 新潟大学, 医歯学系, 助教 (80422608)
|
Project Period (FY) |
2009 – 2011
|
Project Status |
Completed (Fiscal Year 2011)
|
Budget Amount *help |
¥4,550,000 (Direct Cost: ¥3,500,000、Indirect Cost: ¥1,050,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
|
Keywords | 歯周免疫機能学 / 医療・福祉 / 歯学 / 酵素 / 免疫学 / 病理学 |
Research Abstract |
We have reported the 1^<st> report "Gene expression and immunohistochemical protein localization of TIMP-3 and TIMP-in gingival overgrowth and periodontitis-affected gingival tissues" Archs Oral Biology(2009). Then I have received the Academic Senior Investigator's Award for this series of studies in 2009 from Japanese Society of Conservative Dentistry(Review 2010)。The 2^<nd> and 3^<rd> reports :"Microarray and data-mining analyses for specific gene expression in drug-induced gingival overgrowth tissues. Archs Oral Biology(2011)", and "Altered gene expression pattern and specific biological pathways in periodontitis-affected gingival tissues." J Periodont Res(2011) have published in international scientific peer review journals.
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Report
(4 results)
Research Products
(19 results)