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Relationship between tooth loss and risk factors for cancer

Research Project

Project/Area Number 21592645
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Social dentistry
Research InstitutionOsaka University

Principal Investigator

OJIMA Miki  大阪大学, 大学院・歯学研究科, 助教 (20263303)

Co-Investigator(Kenkyū-buntansha) KUBONIWA Masae  大阪大学, 歯学部附属病院, 講師 (00303983)
TANAKA Muneo  大阪大学, 歯学部附属病院, 講師 (90263300)
NISHIDA Nobuko  大阪大学, 歯学部附属病院, 医員 (80456946)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywords歯の喪失 / 歯周病 / 癌 / 食生活 / 栄養 / 炎症 / 歯学 / 疫学 / 喫煙 / 栄養学 / 口腔細菌
Research Abstract

Although several epidemiological studies in medical field have demonstrated the relationship between tooth loss and cancer, underlying mechanisms in the relationship remain unclear. The present study aimed to investigate number of teeth, prosthetic condition, dietary patterns and nutrition, and to determine the relationship between tooth loss status and diet related to digestive cancer. Our results suggested that a reduction in chewing ability caused by tooth loss and no prosthetic treatment might lead to the dietary pattern related to digestive cancer and poor nutrition intake.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (26 results)

All 2012 2011 2010 2009

All Journal Article (12 results) (of which Peer Reviewed: 11 results) Presentation (11 results) Book (3 results)

  • [Journal Article] Necessity and readiness for smoking cessation intervention in dental clinics in Japan2012

    • Author(s)
      Ojima M, Hanioka T, Tanaka H
    • Journal Title

      J Epidemiol

      Volume: 22 Pages: 57-63

    • NAID

      10030213140

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Necessity and Readiness for Smoking Cessation Intervention in Dental Clinics in Japan2012

    • Author(s)
      Miki Ojima
    • Journal Title

      Journal of Epidemiology

      Volume: 22 Issue: 1 Pages: 57-63

    • DOI

      10.2188/jea.JE20110038

    • NAID

      10030213140

    • ISSN
      0917-5040, 1349-9092
    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 全身の健康へのアプローチ-歯肉溝滲出液検査を利用して-予防歯科診療への応用2012

    • Author(s)
      小島美樹
    • Journal Title

      歯界展望

      Volume: 119 Pages: 900-901

    • Related Report
      2011 Annual Research Report
  • [Journal Article] Does secondhand smoke affect the development of dental caries in children? A systematic review2011

    • Author(s)
      Hanioka T, Ojima M, Tanaka K, Yamamoto M
    • Journal Title

      Int J Environ Res Public Health

      Volume: 8 Pages: 1503-19

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Causal assessment of smoking and tooth loss : a systematic review of observational studies2011

    • Author(s)
      Hanioka T, Ojima M, Tanaka K, Matsuo K, Sato F, Tanaka H
    • Journal Title

      BMC Public Health

      Volume: 11 Pages: 22-22

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Causal assessment of smoking and tooth loss : A systematic review of observational studies2011

    • Author(s)
      Takashi Hanioka, Miki Ojima
    • Journal Title

      BMC Public Health

      Volume: (in press 掲載確定)

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Destructive effects of smoking on molecular and genetic factors of periodontal disease2010

    • Author(s)
      Ojima M, Hanioka T
    • Journal Title

      Tob Induc Dis

      Volume: 8 Pages: 4-4

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Intensive smoking-cessation intervention in the dental setting2010

    • Author(s)
      Hanioka T, Ojima M et al
    • Journal Title

      J Dent Res

      Volume: 89 Pages: 66-70

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of a tobacco curriculum on smoking behaviour and attitudes toward smoking in dental students in Japan : a three-year follow-up study2010

    • Author(s)
      Haresaku S, Hanioka T, Yamamoto M, Ojima M
    • Journal Title

      Int Dent J

      Volume: 60 Pages: 99-105

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Genotyping to distinguish microbial pathogenicity in periodontitis2010

    • Author(s)
      Kuboniwa M, Inaba H, Amano A
    • Journal Title

      Periodontol 2000

      Volume: 54 Pages: 136-159

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Subgingival biofilm formation2010

    • Author(s)
      Kuboniwa M, Lamont RJ
    • Journal Title

      Periodontol 2000

      Volume: 52 Pages: 38-52

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Destructive effects of smoking on molecular and genetic factors of periodontal disease2010

    • Author(s)
      Miki Ojima
    • Journal Title

      Tobacco Induced Diseases 8(In press)

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] 歯の喪失と癌の誘発要因との関連性(第1報)-食生活の観点から-2011

    • Author(s)
      小島美樹, 松瀬亮一, 埴岡隆, 前田和彦, 久保庭雅恵
    • Organizer
      第60回日本口腔衛生学会総会
    • Place of Presentation
      松戸
    • Year and Date
      2011-10-09
    • Related Report
      2011 Final Research Report
  • [Presentation] 歯の喪失と癌の誘発要因との関連性(第1報)-食生活の観点から-2011

    • Author(s)
      小島美樹
    • Organizer
      第60回日本口腔衛生学会総会
    • Place of Presentation
      日本大学松戸歯学部
    • Year and Date
      2011-10-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] 若年女性の喫煙状況に関する検討-歯科患者全国調査から2010

    • Author(s)
      小島美樹, 埴岡隆, 青山旬, 尾崎哲則
    • Organizer
      第69回日本公衆衛生学会総会
    • Place of Presentation
      東京
    • Year and Date
      2010-10-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 若年女性の喫煙状況に関する検討-歯科患者全国調査から2010

    • Author(s)
      小島美樹
    • Organizer
      第69回日本公衆衛生学会総会
    • Place of Presentation
      東京国際フォーラム(東京)
    • Year and Date
      2010-10-29
    • Related Report
      2010 Annual Research Report
  • [Presentation] 歯科患者への禁煙介入による医療費削減効果の経年推計2010

    • Author(s)
      小島美樹, 埴岡隆, 尾崎哲則, 青山旬
    • Organizer
      第59回日本口腔衛生学会総会
    • Place of Presentation
      新潟
    • Year and Date
      2010-10-10
    • Related Report
      2011 Final Research Report
  • [Presentation] 歯科患者への禁煙介入による医療費削減効果の経年推計2010

    • Author(s)
      小島美樹
    • Organizer
      第58回日本口腔衛生学会総会
    • Place of Presentation
      朱鷺メッセ(新潟市)
    • Year and Date
      2010-10-10
    • Related Report
      2010 Annual Research Report
  • [Presentation] Smoking status and smoking-attributable treatment needs among dental patients2010

    • Author(s)
      Ojima, M., Hanioka, T., Ozaki, T., Aoyama, H. and Shizukuishi, S
    • Organizer
      88th General Session & Exhibition of the IADR
    • Place of Presentation
      Barcelona(Spain)
    • Year and Date
      2010-07-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Impact of teeth on mortality from pneumonia in elderly patients2010

    • Author(s)
      Terada, K., Ojima, M., Tsuji, T., Kishi, N. and Harada, K
    • Organizer
      88th General Session & Exhibition of the IADR
    • Place of Presentation
      Barcelona(Spain)
    • Year and Date
      2010-07-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Smoking status and smoking-attributable treatment needs among dental patients2010

    • Author(s)
      Miki Ojima
    • Organizer
      88^<th> General Session & Exhibition of the IADR
    • Place of Presentation
      Centre Convencions Internacional Barcelona (Spain)
    • Year and Date
      2010-07-16
    • Related Report
      2010 Annual Research Report
  • [Presentation] 歯科領域での禁煙対策のための歯科受診喫煙者の実態把握2009

    • Author(s)
      小島美樹, 埴岡隆, 青山旬, 尾崎哲則
    • Organizer
      第68回日本公衆衛生学会総会
    • Place of Presentation
      奈良
    • Related Report
      2011 Final Research Report
  • [Presentation] 歯科傷病別の医療需要に及ぼす喫煙の影響2009

    • Author(s)
      小島美樹, 埴岡隆, 尾崎哲則, 青山旬, 雫石聰
    • Organizer
      第58回日本口腔衛生学会総会
    • Place of Presentation
      岐阜
    • Related Report
      2011 Final Research Report
  • [Book] Chapter 5'' Effects of smoking and smoking cessation intervention. In : Periodontal diseases-A Clinician' s Guide(ed. Jane M)2012

    • Author(s)
      Hanioka T, Ojima M, Nakamura M
    • Publisher
      InTech-Open Access Publisher
    • Related Report
      2011 Final Research Report
  • [Book] Chapter 21" Heterotypic Streptococcus gordonii. Porphyromonas gingivalis communities : formation, gene regulation and development" in'' Genomic inquiries into oral bacterial communities''2011

    • Author(s)
      Kuboniwa M, Lamont RJ
    • Publisher
      ASM Press
    • Related Report
      2011 Final Research Report
  • [Book] 歯周病細菌の臓器疾患への影響.健康寿命を延ばす歯科保健医療2009

    • Author(s)
      田中宗雄, 小野高裕
    • Publisher
      医歯薬出版
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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