| Project/Area Number |
21592668
|
|---|
| Research Category |
Grant-in-Aid for Scientific Research (C)
|
| Allocation Type | Single-year Grants |
|---|
| Section | 一般 |
|---|
| Research Field |
Social dentistry
|
|---|
| Research Institution | Kanagawa Dental College |
|---|
Principal Investigator |
MIZUNO Junzo 神奈川歯科大学, 歯学部, 講師 (10308306)
|
|---|
| Co-Investigator(Renkei-kenkyūsha) |
ONOZUKA Minoru 神奈川歯科大学, 歯学部, 教授 (90084780)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥4,290,000 (Direct Cost: ¥3,300,000、Indirect Cost: ¥990,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
|
|---|
| Keywords | 口腔ケア / 超高齢化社会 / 認知機能 / fMRI |
|---|
| Research Abstract |
We examined the interaction between brushing and brain regional activity using fMRI. Toothbrushing(TB) resulted in a bilateral increase in the BOLD signals in the sensorimotor cortex, insula, cingulate cortex, supplementary motor area, and prefrontal cortex. In the supplementary motor area and prefrontal cortex, the BOLD signals in the right side were greater than those in the left side. In our neurocognitive test study, TB caused increases in the scores in the MMSE, DST, and the KHT, but an age-dependency was seen in the MMSE and KHT. Furthermore, TB significantly enhanced activation in the prefrontal cortex during KHT. These findings suggest that TB produces an increase in neurocognitive function in the elderly, due to neuronal activation in the prefrontal cortex.
|
