| Project/Area Number |
21592676
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
|
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| Research Institution | Yamagata University (2011)
Tohoku University (2009-2010) |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
MARUYAMA Ryoko 東北大学, 大学院・医学系研究科, 教授 (10275498)
MINAMI Yuko 東北大学, 大学院・医学系研究科, 教授 (60239316)
WATANABE Ikue 東北大学, 大学院・医学系研究科, 助教 (30323124)
KANNO Emi 東北大学, 大学院・医学系研究科, 助教 (10431595)
|
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| Co-Investigator(Renkei-kenkyūsha) |
NAKANO Akihiko 東京大学, 大学院・理学系研究科, 教授 (90142140)
|
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2009: ¥3,120,000 (Direct Cost: ¥2,400,000、Indirect Cost: ¥720,000)
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| Keywords | 放射線治療 / DNA修復 / 乳がん / 看護アセスメント / DNA損傷修復 / DNA損傷修復因子 |
|---|
| Research Abstract |
The screening for detecting genes which involved in breast cancer development revealed 25 related ones. The five of them were unknown as DNA repair factors. Also, we characterized a novel repair gene, MDT1, which we isolated previously, and the experiment showed that MDT1 has a role for the protein metabolism.
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