| Project/Area Number |
21592683
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Fundamental nursing
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| Research Institution | Chiba University |
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Principal Investigator |
OKADA Shinobu 千葉大学, 大学院・看護学研究科, 教授 (00334178)
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| Co-Investigator(Kenkyū-buntansha) |
NISHIO Junko 千葉大学, 大学院・看護学研究科, 技術職員 (30396692)
KAMEI Katsuhiko 千葉大学, 真菌医学研究センター, 教授 (10214545)
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| Research Collaborator |
OGAWA Toshiko 千葉大学, 大学院・看護学研究科, 博士後期課程大学院生
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,420,000 (Direct Cost: ¥3,400,000、Indirect Cost: ¥1,020,000)
Fiscal Year 2011: ¥390,000 (Direct Cost: ¥300,000、Indirect Cost: ¥90,000)
Fiscal Year 2010: ¥2,340,000 (Direct Cost: ¥1,800,000、Indirect Cost: ¥540,000)
Fiscal Year 2009: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
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| Keywords | 口腔ケア / ゴマ油 / 口腔カンジダ症 / セサミン / 口腔乾燥 |
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| Research Abstract |
Sesame oil inhibited the growth of both mycelial and yeast form of C. albicans. However, the effect differed between strains. The effect of oral cleansing with sesame oil was not clarified in murine oral candidisis model. Application of sesame oil kept moisture of oral mucosa in healthy adults. No discomfort was not reported after application of sesame oil to oral cavity in healthy adult and elderly volunteers. Two elderly who required nursing care in home received oral cleansing with sesame oil three times a day. Twenty days after the intervention improvement of color and moisture of oral mucosa and decrease in number of gram-negative rods in oral cavity were observed in one participant.
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