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Development of specific gene activation method using polyamide-transcription factor conjugates

Research Project

Project/Area Number 21603008
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Chemical biology
Research InstitutionKyoto University

Principal Investigator

ENDO Masayuki  京都大学, 物質細胞統合システム拠点, 准教授 (70335389)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,940,000 (Direct Cost: ¥3,800,000、Indirect Cost: ¥1,140,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Keywordsエピジェネティック制御 / DNAナノ構造 / ヌクレオソーム / 原子間力顕微鏡 / ポリアミド / ヒストン / DNA修復酵素 / 1分子イメージング
Research Abstract

We tried to investigate the regulation of gene expression using synthetic pyrrole-imidazole polyamide. For the investigation of the mechanism of epigenetic regulation, we developed the imaging method for nucleosome and related enzymes. For direct visualization of the nucleosome, we constructed the single molecule observation system using the designed DNA nanostructures. We successfully visualized the sequence-selectivity of functionalized polyamide in the designed DNA nanostructure. We also constructed the single-molecule observation system for the behavior of enzymes using high-speed atomic force microscopy. Using this system, we successfully captured the nucleosome to the DNA nanoscaffold, and observed its behavior at the single-molecule level.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (69 results)

All 2012 2011 2010 2009

All Journal Article (31 results) (of which Peer Reviewed: 31 results) Presentation (33 results) Book (5 results)

  • [Journal Article] Transcription Regulation System Mediated by Mechanical Operation of DNA Nanostructure2012

    • Author(s)
      M. Endo, R. Miyazaki, T. Emura, K. Hidaka, H. Sugiyama
    • Journal Title

      J. Am. Chem. Soc

      Volume: 134 Issue: 6 Pages: 2852-2855

    • DOI

      10.1021/ja2074856

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Sequence-Selective Single-Molecule Alkylation with a Pyrrole-Imidazole Polyamide Visualized in a DNA Nanoscaffold2012

    • Author(s)
      T. Yoshidome, M. Endo, G. Kashiwazaki, K. Hidaka, T. Bando, H. Sugiyama
    • Journal Title

      J. Am. Chem. Soc

      Volume: 134 Issue: 10 Pages: 4654-4660

    • DOI

      10.1021/ja209023u

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A DNA-based molecular motor that can navigate a network of tracks2012

    • Author(s)
      S Wickham, J Bath, Y Katsuda, M Endo, K Hidaka, H Sugiyama, AJ Turberfield
    • Journal Title

      Nature Nanotech

      Volume: 7 Issue: 3 Pages: 169-173

    • DOI

      10.1038/nnano.2011.253

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Single-Molecule Analysis Using DNA Origami2012

    • Author(s)
      A.Rajendran, M.Enao, H.Sugiyama
    • Journal Title

      Angew.Chem.Int.Ed.

      Volume: 51 Issue: 4 Pages: 874-890

    • DOI

      10.1002/anie.201102113

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Zinc-Finger Proteins for Site-Specific Protein Positioning on DNA-Origami Structures2012

    • Author(s)
      E.Nakata, FF Liew, C Uwatoko, S Kiyonaka, Y Mori, Y Katsuda, M Endo, H Sugiyama, T Morii
    • Journal Title

      Angew Chem Int Ed

      Volume: 51 Issue: 10 Pages: 2421-2424

    • DOI

      10.1002/anie.201108199

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Structure and Functional Analysis of Proteins by High-Speed Atomic Force Microscopy2012

    • Author(s)
      A. Rajendran, M. Endo, H. Sugiyama
    • Journal Title

      Advances in Protein Chemistry and Structural Biology

      Volume: 87 Pages: 5-55

    • DOI

      10.1016/b978-0-12-398312-1.00002-0

    • ISBN
      9780123983121
    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] DNA Origami : Synthesis and Self-Assembly2012

    • Author(s)
      A.Rajendran, M.Kndo, H.Sugiyama
    • Journal Title

      Curr.Protoc.Nucleic Acid Chem.

      Volume: 48 Issue: 1

    • DOI

      10.1002/0471142700.nc1209s48

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Photo-cross-linking-assisted thermal stability of DNA origami structures and its application for higher-temperature self-assembly2011

    • Author(s)
      A.Rajendran, M.Endo, Y.Eatsuda, K.Hidaka, H.Sugiyama
    • Journal Title

      J.Am.Chem.Soc.

      Volume: 133 Issue: 37 Pages: 14488-91

    • DOI

      10.1021/ja204546h

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Programmed placement of gold nanoparticles onto a slit-type DNA origami scaffold2011

    • Author(s)
      M. Endo, Y. Yang, T. Emura, K. Hidaka, H. Sugiyama
    • Journal Title

      Chem. Commun

      Volume: 47 Issue: 38 Pages: 10743-10745

    • DOI

      10.1039/c1cc13984c

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Direct observation of stepwise movement of a synthetic molecular transporter2011

    • Author(s)
      S. F. J. Wickham, M. Endo, Y. Katsuda, K. Hidaka, J. Bath, H. Sugiyama, A. J Turberfield
    • Journal Title

      Nature Nanotechnology

      Volume: 6 Issue: 3 Pages: 166-169

    • DOI

      10.1038/nnano.2010.284

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two-dimensional DNA origami assemblies using a four-way connector2011

    • Author(s)
      M. Endo, T. Sugita, A. Rajendran, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Journal Title

      Chem. Commun

      Volume: 47 Issue: 11 Pages: 3213-3215

    • DOI

      10.1039/c0cc05306f

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Programmed Two-Dimensional Self-Assembly of Multiple DNA Origami Jigsaw Pieces2011

    • Author(s)
      A. Rajendran, M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Journal Title

      ACS Nano

      Volume: 5 Issue: 1 Pages: 665-671

    • DOI

      10.1021/nn1031627

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Direct AFM Observation of an Opening Event of a DNA Cuboid Constructed via a Prism Structure2011

    • Author(s)
      M. Endo, K. Hidaka, H. Sugiyama
    • Journal Title

      Org. Biomol. Chem

      Volume: 9 Issue: 7 Pages: 2075-2077

    • DOI

      10.1039/c0ob01093f

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recent Progress in DNA origami technology2011

    • Author(s)
      M. Endo, H. Sugiyama
    • Journal Title

      Curr. Protoc. Nucleic Acid Chem

      Volume: 45 Issue: 1

    • DOI

      10.1002/0471142700.nc1208s45

    • Related Report
      2011 Annual Research Report 2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Programmed Two-Dimensional Self-Assembly of Multiple DNA Origami Jigsaw Pieces.2011

    • Author(s)
      A.Rajendran, M.Endo, Y.Katsuda, K.Hidaka, H.Sugiyama
    • Journal Title

      ACS Nano

      Volume: 5 Pages: 665-671

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct observation of stepwise movement of a synthetic molecular transporter.2011

    • Author(s)
      S.Wickham, M.Endo, Y.Katsuda, K.Hidaka, J.Bath, H.Sugiyama, A.J.Turberfield
    • Journal Title

      Nature Nanotechnology

      Volume: 6 Pages: 166-169

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two-dimensional DNA origami assemblies using a four-way connector.2011

    • Author(s)
      M.Endo, T.Sugita, A.Rajendran, Y.Katsuda, T.Emura, K.Hidaka, H.Sugiyama
    • Journal Title

      Chemical Communications

      Volume: 47 Pages: 3213-3215

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Direct AFM Observation of an Opening Event of a DNA Cuboid Constructed via a Prism Structure.2011

    • Author(s)
      M.Endo, K.Hidaka, H.Sugiyama
    • Journal Title

      Organic & Biomolecular Chemistry

      Volume: 9 Pages: 2075-2077

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of DNA Methylation Using Different Tensions of Double Strands Constructed in a Defined DNA Nanostructure2010

    • Author(s)
      M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Journal Title

      J. Am. Chem. Soc

      Volume: 132 Issue: 5 Pages: 1592-1597

    • DOI

      10.1021/ja907649w

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] A versatile DNA nanochip for direct analysis of DNA base-excision repair2010

    • Author(s)
      M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Journal Title

      Angew. Chem. Int. Ed

      Volume: 49 Issue: 49 Pages: 9412-9416

    • DOI

      10.1002/anie.201003604

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of Dynamic Conformational Switching of the G-Quadruplex in a DNA Nanostructure2010

    • Author(s)
      Y. Sannohe, M. Endo, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Journal Title

      J. Am. Chem. Soc

      Volume: 132 Issue: 46 Pages: 16311-16313

    • DOI

      10.1021/ja1058907

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Programmed-Assembly System Using DNA Jigsaw Pieces2010

    • Author(s)
      M. Endo, T. Sugita, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Journal Title

      Chem. Eur. J.

      Volume: 16 Issue: 18 Pages: 5362-5368

    • DOI

      10.1002/chem.200903057

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of DNA Methylation Using Different Tensions of Double Strands Constructed in a Defined DNA Nanostructure.2010

    • Author(s)
      M.Endo, Y.Katsuda, K.Hidaka, H.Sugiyama
    • Journal Title

      Journal of the American Chemical Society

      Volume: 132 Pages: 1592-1597

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Programmed-Assembly System Using DNA Jigsaw Pieces.2010

    • Author(s)
      M.Endo, T.Sugita, Y.Katsuda, K.Hidaka, H.Sugiyama
    • Journal Title

      Chemistry, A European Journal,, (2010)

      Volume: 16 Pages: 5362-5368

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Visualization of Dynamic Conformational Switching of the G-Quadruplex in a DNA Nanostructure.2010

    • Author(s)
      Y.Sannohe, M.Endo, Y.Katsuda, K.Hidaka, H.Sugiyama
    • Journal Title

      Journal of the American Chemical Society

      Volume: 132 Pages: 16311-16313

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A versatile DNA nanochip for direct analysis of DNA base-excision repair.2010

    • Author(s)
      M.Endo, Y.Katsuda, K.Hidaka, H.Sugiyama
    • Journal Title

      Angewandte Chemie, International Edition

      Volume: 49 Pages: 9412-9416

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Regulation of DNA Methylation Using Different Tensions of Double Strands Constructed in a Defined DNA Nanostructure.2010

    • Author(s)
      M.Endo, Y.Katsuda, K.Hidaka, H.Sugiyama,
    • Journal Title

      Journal of the American Chemical Society 132

      Pages: 1592-1597

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms2009

    • Author(s)
      M. Endo, K. Hidaka, T. Kato, K. Namba, H. Sugiyama
    • Journal Title

      J. Am. Chem. Soc

      Volume: 131 Issue: 43 Pages: 15570-15571

    • DOI

      10.1021/ja904252e

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Chemical Approaches to DNA Nanotechnology2009

    • Author(s)
      M. Endo, H. Sugiyama
    • Journal Title

      ChemBioChem

      Volume: 10 Issue: 15 Pages: 2420-2443

    • DOI

      10.1002/cbic.200900286

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] DNA Prism Structures Constructed by Folding of Multiple Rectangular Arms.2009

    • Author(s)
      M.Endo, K.Hidaka, T.Kato, K.Namba, H.Sugiyama
    • Journal Title

      Journal of the American Chemical Society 131

      Pages: 15570-15571

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Chemical Approaches to DNA Nanotechnology2009

    • Author(s)
      M.Endo, H.Sugiyama
    • Journal Title

      ChemBioChem 10

      Pages: 2420-2443

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] DNAナノ構造変換を利用した転写の制御2012

    • Author(s)
      遠藤政幸、宮崎亮次、江村智子、日高久美、杉山弘
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜
    • Year and Date
      2012-03-28
    • Related Report
      2011 Final Research Report
  • [Presentation] DNAナノ構造変換を利用した転写の制御2012

    • Author(s)
      遠藤政幸、宮崎亮次、江村智子、日高久美、杉山弘
    • Organizer
      日本化学会第92春季年会
    • Place of Presentation
      横浜市
    • Year and Date
      2012-03-28
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNAナノ構造体の生体反応への応用2011

    • Author(s)
      遠藤政幸
    • Organizer
      創剤フォーラム若手研究会シンポジウム
    • Place of Presentation
      京都大学薬学部、京都
    • Year and Date
      2011-11-19
    • Related Report
      2011 Final Research Report
  • [Presentation] DNAナノ構造体の生体反応への応用2011

    • Author(s)
      遠藤政幸
    • Organizer
      創剤フォーラム若手研究会シンポジウム
    • Place of Presentation
      京都市(招待講演)
    • Year and Date
      2011-11-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] AFM-based Imaging of the Movement of Biomolecules in the Designed DNA Nanostructures2011

    • Author(s)
      M. Endo
    • Organizer
      5th Annual Symposium on Nanobiotechnology, Seoul NanoHealth 2011
    • Place of Presentation
      Yonsei University, Seoul, Korea
    • Year and Date
      2011-11-17
    • Related Report
      2011 Final Research Report
  • [Presentation] AFM-based Imaging of the Movement of Biomolecules in the Designed DNA Nanostructures2011

    • Author(s)
      遠藤政幸
    • Organizer
      5th Annual Symposium on Nanobiotechnology, Seoul NanoHealth 2011
    • Place of Presentation
      Seoul, Korea(招待講演)
    • Year and Date
      2011-11-17
    • Related Report
      2011 Annual Research Report
  • [Presentation] Designed DNA Nanostructures for Assembly, Functionalization, and Visualization. POSTECH AMS Symposium on Nanotechnology2011

    • Author(s)
      M. Endo
    • Organizer
      Pohang University of Science and Technology
    • Place of Presentation
      Pohang, Korea
    • Year and Date
      2011-11-16
    • Related Report
      2011 Final Research Report
  • [Presentation] Designed DNA Nanostructures for Assembly, Functionalization, and Visualization2011

    • Author(s)
      遠藤政幸
    • Organizer
      POSTECH AMS Symposium on Nanotechnology
    • Place of Presentation
      Pohang, Korea(招待講演)
    • Year and Date
      2011-11-16
    • Related Report
      2011 Annual Research Report
  • [Presentation] Direct Observation of DNA recombination in the DNA nanoscaffold2011

    • Author(s)
      M. Endo, Y. Katsuda, K. Ou, K. Hidaka, H. Sugiyama
    • Organizer
      The 38^<th> International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      Sapporo
    • Year and Date
      2011-11-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Direct Observation of DNA recombination in the DNA nanoscaffold2011

    • Author(s)
      M.Endo,Y.Katsuda, K.Ou, K.Hidaka, H.Sugiyama
    • Organizer
      The 38th International Symposium on Nucleic Acid Chemistry
    • Place of Presentation
      札幌市
    • Year and Date
      2011-11-09
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNAナノマシーンの1分子運動の可視化2011

    • Author(s)
      遠藤政幸
    • Organizer
      第84回日本生化学会大会シンポジウム
    • Place of Presentation
      京都
    • Year and Date
      2011-09-21
    • Related Report
      2011 Final Research Report
  • [Presentation] DNAナノマシーンの1分子運動の可視化2011

    • Author(s)
      遠藤政幸
    • Organizer
      第84回日本生化学会大会シンポジウム「分子ロボティクス」
    • Place of Presentation
      京都市(招待講演)
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNAオリガミ上でのDNA分子の移動の精密な操作2011

    • Author(s)
      遠藤政幸、勝田陽介、日高久美、S. Wickham, J. Bath, A. D. Turberfield, 杉山弘
    • Organizer
      DNAオリガミ上でのDNA分子の移動の精密な操作
    • Place of Presentation
      東京
    • Year and Date
      2011-05-25
    • Related Report
      2011 Final Research Report
  • [Presentation] DNAオリガミ上でのDNA分子の移動の精密な操作2011

    • Author(s)
      遠藤政幸、勝田陽介、日高久美、S.F.J.Wickham, J.Bath, A.D.Turberfield, 杉山弘
    • Organizer
      ケミカルバイオロジー学会第6回年会
    • Place of Presentation
      東京都
    • Year and Date
      2011-05-25
    • Related Report
      2011 Annual Research Report
  • [Presentation] Programmed assembly of DNA nanostructures using designed DNAorigami tiles2011

    • Author(s)
      M.Endo, A.Rajendran, T.Sugita, Y.Katsuda, K.Hidaka, H.Sugiyama
    • Organizer
      8th Conference on the Foundations of Nanoscience 2011
    • Place of Presentation
      Utah、USA
    • Year and Date
      2011-04-19
    • Related Report
      2011 Annual Research Report
  • [Presentation] DNAオリガミ法によるナノ構造体の作製と生体分子の動的挙動の1分子観察2011

    • Author(s)
      遠藤政幸
    • Organizer
      単分子エレクトロニクスの現状認識と近未来実現へ向けての中核体制構築
    • Place of Presentation
      国際高等研究所、京都
    • Year and Date
      2011-02-25
    • Related Report
      2011 Final Research Report
  • [Presentation] DNAオリガミ法によるナノ構造体の作成と生体分子の動的挙動の1分子観察2011

    • Author(s)
      遠藤政幸
    • Organizer
      国際高等研究所「単分子エレクトロニクスの現状認識と近未来実現へ向けての中核体制構築」
    • Place of Presentation
      京都(招待講演)
    • Year and Date
      2011-02-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] Programmed assembly of DNA nanostructures using designed DNAorigami tiles2011

    • Author(s)
      M. Endo, A. Rajendran, T. Sugita, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Organizer
      8th Conference on the Foundations of Nanoscience 2011
    • Place of Presentation
      Snowbird UT, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Visualization of single molecular movement in the designed DNA nano-space2010

    • Author(s)
      M. Endo
    • Organizer
      The SSI 2010 International Symposium
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-11-24
    • Related Report
      2011 Final Research Report
  • [Presentation] Visualization of single molecular movement in the designed DNA nano-space2010

    • Author(s)
      M.Endo
    • Organizer
      The SSI 2010 International Symposium
    • Place of Presentation
      Kyoto(招待講演)
    • Year and Date
      2010-11-24
    • Related Report
      2010 Annual Research Report
  • [Presentation] Direct observation of stepwise movement of DNA nanomachine walking along the track constructed on a DNA origami scaffold2010

    • Author(s)
      M. Endo, Y. Katsuda, K. Hidaka, S. F. J. Wickham, J. Bath, A. J. Turberfield, H. Sugiyama
    • Organizer
      The 37th Symposium on Nucleic Acids Chemistry 2010
    • Place of Presentation
      Yokohama
    • Year and Date
      2010-11-12
    • Related Report
      2011 Final Research Report
  • [Presentation] Direct observation of stepwise movement of DNA nanomachine walking along the track constructed on a DNA origami scaffold.2010

    • Author(s)
      M.Endo, Y.Katsuda, K.Hidaka, S.Wickham, J.Bath, A.J.Turberfield, H.Sugiyama
    • Organizer
      The 37th Symposium on Nucleic Acids Chemistry 2010
    • Place of Presentation
      Yokohama
    • Year and Date
      2010-11-12
    • Related Report
      2010 Annual Research Report
  • [Presentation] Visualization of single molecular movement on the DNA origami scaffold using high-speed AFM2010

    • Author(s)
      M. Endo
    • Organizer
      The 8th iCeMS International Symposium
    • Place of Presentation
      Kyoto
    • Year and Date
      2010-11-09
    • Related Report
      2011 Final Research Report
  • [Presentation] Visualization of single molecular movement on the DNA origami scaffold using high-speed AFM.2010

    • Author(s)
      M.Endo
    • Organizer
      The 8th iCeMS International Symposium
    • Place of Presentation
      Kyoto(招待講演)
    • Year and Date
      2010-11-09
    • Related Report
      2010 Annual Research Report
  • [Presentation] DNA修復反応を観察するDNAナノチップの開発2010

    • Author(s)
      遠藤政幸、勝田陽介、日高久美、杉山弘
    • Organizer
      ケミカルバイオロジー学会第5回年会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-19
    • Related Report
      2011 Final Research Report
  • [Presentation] DNA修復反応を観察するDNAナノチップの開発2010

    • Author(s)
      遠藤政幸・勝田陽介・日高久美・杉山弘
    • Organizer
      ケミカルバイオロジー学会 第5回年会
    • Place of Presentation
      横浜
    • Year and Date
      2010-05-19
    • Related Report
      2010 Annual Research Report
  • [Presentation] Programmed self-assembly of DNA jigsaw pieces.2010

    • Author(s)
      M.Endo, H.Sugiyama
    • Organizer
      7th Conference on the Foundations of Nanoscience 2010
    • Place of Presentation
      Snowbird, UT, USA
    • Year and Date
      2010-04-28
    • Related Report
      2010 Annual Research Report
  • [Presentation] 2次元DNAオリガミ構造の折りたたみによる3次元ナノ構造の構築2010

    • Author(s)
      遠藤政幸、日高久美、杉山弘
    • Organizer
      日本化学会第90春季年会
    • Place of Presentation
      大阪
    • Year and Date
      2010-03-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Direct Observation of Single Molercular Beavior of T7 RNA Polymerase on the Defined DNA Nanostructure2010

    • Author(s)
      M. Endo, K. Tatsumi, K. Terushima, Y. Katsuda, K. Hidaka, H. Sugiyama
    • Organizer
      The International Chemical Congress of Pacific Basin Societies(PACIFICHEM)
    • Place of Presentation
      Hawaii
    • Related Report
      2011 Final Research Report
  • [Presentation] Sugiyama, Programmed self-assembly of DNA jigsaw pieces2010

    • Author(s)
      M. Endo, H.
    • Organizer
      7th Conference on the Foundations of Nanoscience 2010(FNANO10)
    • Place of Presentation
      Snowbird, UT, USA
    • Related Report
      2011 Final Research Report
  • [Presentation] Preparation of DNA scaffolds for the 3D-nanostructure construction2009

    • Author(s)
      M. Endo, H. Sugiyama
    • Organizer
      The 6th International Symposium on Nucleic Acids Chemistry and 36th Symposium on Nucleic Acids Chemistry 2009
    • Place of Presentation
      Takayama
    • Year and Date
      2009-10-01
    • Related Report
      2011 Final Research Report
  • [Presentation] Three-dimensional DNA Nanostructures Constructed by Folding of Multiple Rectangles.2009

    • Author(s)
      M.Endo, H.Sugiyama
    • Organizer
      The 6^<th> International Symposium Nucleic Acids
    • Place of Presentation
      岐阜県高山市
    • Year and Date
      2009-10-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Design and Construction of DNA Nanostructure for Integration of Molecules2009

    • Author(s)
      M. Endo
    • Organizer
      The 5th iCeMS International Symposium
    • Place of Presentation
      Kyoto
    • Year and Date
      2009-06-27
    • Related Report
      2011 Final Research Report
  • [Book] DNAオリガミによる1分子観察系の構築実験医学2012

    • Author(s)
      遠藤政幸、杉山弘
    • Related Report
      2011 Final Research Report
  • [Book] DNAオリガミ構造体と1分子観察への応用2012

    • Author(s)
      遠藤政幸、杉山弘
    • Related Report
      2011 Final Research Report
  • [Book] DNAオリガミによるメゾスケール多次元構造の構築とナノ空間での機能発現2011

    • Author(s)
      遠藤政幸、杉山弘
    • Related Report
      2011 Final Research Report
  • [Book] DNAオリガミ法による多次元構造体の構築と高次機能化2011

    • Author(s)
      遠藤政幸、杉山弘
    • Related Report
      2011 Final Research Report
  • [Book] DNAナノ構造の設計・構築とその応用2010

    • Author(s)
      遠藤政幸、杉山弘
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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