| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Research Abstract |
Elucidation of new anti-tumor and anti-HIV target proteins has been investigated by using the probe molecules derived from the bioactive natural products, peumusolide and osthol, found by our group. Consequently, we disclosed the respective probe molecules not only containing the diardine-biotin unit to capture and purify target proteins under photo-irradiation but also inhibiting nuclear-export of MEK and Rev potently.
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