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New QC・QA method with traceable point-like sources for PET

Research Project

Project/Area Number 21611007
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Medical Physics/Radiological Technology
Research InstitutionKitasato University

Principal Investigator

HASEGAWA Tomoyuki  北里大学, 医療衛生学部, 准教授 (10276181)

Research Collaborator ODA Keiichi  東京都健康長寿医療センター研究所, 研究員 (70224235)
WADA Yasuhiro  理化学研究所, 分子イメージング科学研究センター, 副チームリーダー (40382197)
SATO Yasushi  産業技術総合研究所, 計測標準研究部門, 研究員 (90357153)
MURAYAMA Hideo  放射線医学総合研究所, 研究員 (50166310)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥4,160,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥960,000)
Fiscal Year 2011: ¥780,000 (Direct Cost: ¥600,000、Indirect Cost: ¥180,000)
Fiscal Year 2010: ¥1,430,000 (Direct Cost: ¥1,100,000、Indirect Cost: ¥330,000)
Fiscal Year 2009: ¥1,950,000 (Direct Cost: ¥1,500,000、Indirect Cost: ¥450,000)
Keywords医学物理学 / 放射線物理学 / 品質管理 / 校正 / 標準化 / 点状線源 / PET / 定量性 / 点状放射線源 / トレーサビリティ / クロスキャリブレーション / 性能評価
Research Abstract

Quality control and quality assurance(QC・QA) are crucial for accurate quantification of PET imaging. In order to improve the reliability and convenience of the methodology for determining calibration factors and for evaluating the quantitative aspects of physics characteristics of PET scanners, a set of new methods based on the use of new traceable point-like sources has been developed in this research project.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (50 results)

All 2012 2011 2010 2009

All Journal Article (12 results) (of which Peer Reviewed: 12 results) Presentation (38 results)

  • [Journal Article] Novel point-like^<68> Ge/^<68> Ga radioactive source with spherical positron absorber2012

    • Author(s)
      T. Hasegawa, K. Oda, T. Yamada, M. Matsumoto, Y. Sato, H. Murayama, H. Takei
    • Journal Title

      IEEE Trans. Nucl. Sci.

      Volume: 59 Pages: 24-29

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Novel point-like ^<68>Ge/^<68>Ga radioactive source with spherical positron absorber2012

    • Author(s)
      T.Hasegaw, et al, 他6名
    • Journal Title

      IEEE Trans.Nucl.Sci.

      Volume: 59 Pages: 24-29

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Semi-quantitative and simulation analyses of effects of gamma rays on determination of calibration factors of PET scanners with point-like^<22> Na sources2011

    • Author(s)
      T. Hasegawa, Y. Sato, K. Oda, Y. Wada, H. Murayama, T. Yamada
    • Journal Title

      Phys Med Biol

      Volume: 56 Pages: 6031-45

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of annihilation photons emitted from new types of point-like^<22> Na radioactive sources with symmetric absorber designs2011

    • Author(s)
      T. Hasegawa, Y. Sato, T. Yamada, K. Oda, Y. Wada, E. i Yoshida, H. Murayama, H. Takei
    • Journal Title

      IEEE Trans. Nucl. Sci.

      Volume: 58 Pages: 43-50

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Semi-quantitative and simulation analyses of effects of gamma rays on determination of calibration factors of PET scanners with point-like ^<22>Na sources2011

    • Author(s)
      T.Hasegaw, et al, 他5名
    • Journal Title

      Phys Med Biol

      Volume: 56 Pages: 6031-6045

    • Related Report
      2011 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Characteristics of annihilation photons emitted from new types of point-like ^<22>Na radioactive sources with symmetric absorber designs2011

    • Author(s)
      T.Hasegawa, et al.
    • Journal Title

      IEEE Trans Nucl Sci

      Volume: 58 Pages: 43-50

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] がん診断を支援する核医学イメージング機器-原理と実績-2011

    • Author(s)
      長谷川智之
    • Journal Title

      応用物理学会誌

      Volume: 80 Pages: 103-109

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A practical method of determining cross calibration factors of PET scanners by moving a point-like^<22> Na radioactive source2010

    • Author(s)
      T. Hasegawa, K. Oda, Y. Wada, Y. Sato, T. Yamada, E. Yoshida, H. Murayama, K. Saito, T. Takeda, K. Kikuchi
    • Journal Title

      Ann Nucl Med

      Volume: 24 Pages: 655-661

    • NAID

      10027659516

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Monte Carlo simulation of the standardization of^<22> Na using scintillation detector array2010

    • Author(s)
      Y. Sato, H. Murayama, T. Yamada, T. Hasegawa, K. Oda, Y. Unno, A. Yunoki
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 68 Pages: 1354-1357

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Point-like radioactive source with multiple absorber capsules for evaluating PET scanners2010

    • Author(s)
      T. Hasegawa, E. Yoshida, Y. Sato, K. Oda, T. Yamada, H. Murayama, T. Yamaya, Y. Wada, K. Saito
    • Journal Title

      Ann Nucl Med

      Volume: 24 Pages: 427-432

    • NAID

      10027658999

    • Related Report
      2011 Final Research Report 2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Monte Carlo simulation of the standardization of ^<22>Na using scintillation detector arrays2010

    • Author(s)
      Y.Sato, et al.
    • Journal Title

      Applied Radiation and Isotopes

      Volume: 68 Pages: 1354-1357

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] A practical method of determining cross calibration factors of PET scanners by moving a point-like ^<22>Na radioactive source2010

    • Author(s)
      T.Hasegawa, et al.
    • Journal Title

      Ann Nucl Med

      Volume: 24 Pages: 655-661

    • NAID

      10027659516

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Presentation] PET装置の定量性校正・評価のための新しいGe-68/Ga-68点状線源2011

    • Author(s)
      長谷川智之, 他8名
    • Organizer
      第51回日本核医学会
    • Place of Presentation
      つくば市
    • Year and Date
      2011-10-29
    • Related Report
      2011 Final Research Report
  • [Presentation] PET装置の定量性校正・評価のための新しいGe-68/Ga-68点状線源2011

    • Author(s)
      長谷川智之
    • Organizer
      第51回日本核医学会
    • Place of Presentation
      つくば国際会議場(つくば市)
    • Year and Date
      2011-10-29
    • Related Report
      2011 Annual Research Report
  • [Presentation] Calibration of PET scanners with a new traceable point-like Ge68/Ga68 source2011

    • Author(s)
      T. Hasegawa, 他9名
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Valencia
    • Year and Date
      2011-10-27
    • Related Report
      2011 Final Research Report
  • [Presentation] Calibration of PET scanners with a new traceable point-like Ge68/Ga68 source2011

    • Author(s)
      T.Hasegawa
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Valencia Conference Center (Valencia)
    • Year and Date
      2011-10-27
    • Related Report
      2011 Annual Research Report
  • [Presentation] New calibration scheme for PET scanners with new traceable point-like radioactive sources2011

    • Author(s)
      T.Hasegawa
    • Organizer
      Japan Korea Joint Meeting on Medical Physics
    • Place of Presentation
      Centennial Hall Kyushu University School of Medicine (Fukuoka)
    • Year and Date
      2011-10-01
    • Related Report
      2011 Annual Research Report
  • [Presentation] New calibration scheme for PET scanners with new traceable point-like radioactive sources2011

    • Author(s)
      T. Hasegawa, 他13名
    • Organizer
      Japan Korea Joint Meeting on Medical Physics
    • Place of Presentation
      Fukuoka
    • Year and Date
      2011-09-29
    • Related Report
      2011 Final Research Report
  • [Presentation] Efficiency fitting for TDCR measurement data using polynomial approximation and the newton raphson method2011

    • Author(s)
      Y. Sato, T. Hasegawa, 他9名
    • Organizer
      18th International Conference on Radionuclide Metrology and its Applications
    • Place of Presentation
      Tsukuba
    • Year and Date
      2011-09-21
    • Related Report
      2011 Final Research Report
  • [Presentation] Efficiency fitting for TDCR measurement data using polynomial approximation and the newton raphson method2011

    • Author(s)
      Y.Sato(研究協力者)
    • Organizer
      18th International Conference on Radionuclide Metrology and its Applications
    • Place of Presentation
      International Congress Center (Tsukuba)
    • Year and Date
      2011-09-21
    • Related Report
      2011 Annual Research Report
  • [Presentation] 点状線源を用いたPET装置の定量性評価・校正法の開発: JSMP研究援助課題成果報告2011

    • Author(s)
      長谷川智之, 他9名
    • Organizer
      第101回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-04-07
    • Related Report
      2011 Final Research Report
  • [Presentation] PET装置校正用点線源の放射能絶対測定におけるシンチレータの影響2011

    • Author(s)
      佐藤泰、長谷川智之, 他10名
    • Organizer
      第101回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2011-04-07
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源を用いたPET装置の定量性評価・校正法の開発:JSMP研究援助課題成果報告2011

    • Author(s)
      長谷川智之
    • Organizer
      第101回日本医学物理学会学術大会
    • Place of Presentation
      (臨時Web開催)
    • Year and Date
      2011-04-07
    • Related Report
      2011 Annual Research Report
  • [Presentation] 点状線源によるPET装置のクロスキャリブレーション・ファクタの確認と補正2010

    • Author(s)
      織田圭一、長谷川智之, 他4名
    • Organizer
      第50回日本核医学会
    • Place of Presentation
      大宮
    • Year and Date
      2010-11-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源によるPET装置の日内変動測定2010

    • Author(s)
      織田圭一、長谷川智之, 他4名
    • Organizer
      第50回日本核医学会
    • Place of Presentation
      大宮
    • Year and Date
      2010-11-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源を用いたPET装置の新しい定量性校正・評価法2010

    • Author(s)
      長谷川智之, 他9名
    • Organizer
      第50回日本核医学会
    • Place of Presentation
      大宮
    • Year and Date
      2010-11-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源を用いたPET装置の新しい定量性校正・評価法2010

    • Author(s)
      長谷川智之, 他
    • Organizer
      日本核医学会第50回大会
    • Place of Presentation
      大宮ソニックシティ(大宮)
    • Year and Date
      2010-11-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 点状線源によるPET装置の日内変動測定2010

    • Author(s)
      織田圭一, 他
    • Organizer
      日本核医学会第50回大会
    • Place of Presentation
      大宮ソニックシティ(大宮)
    • Year and Date
      2010-11-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] 点状線源によるPET装置のクロスキャリブレーション・ファクタの確認と補正2010

    • Author(s)
      織田圭一, 他
    • Organizer
      日本核医学会第50回大会
    • Place of Presentation
      大宮ソニックシティ(大宮)
    • Year and Date
      2010-11-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] New calibration method using point-like radioactive sources for PET scanners2010

    • Author(s)
      T. Hasegawa, 他7名
    • Organizer
      IEEE Med Imag Conference
    • Place of Presentation
      Knoxville
    • Year and Date
      2010-11-05
    • Related Report
      2011 Final Research Report
  • [Presentation] Examination of a standardization method for^<22> Na sealed point sources under several measurement conditions2010

    • Author(s)
      Y. Sato, T. Hasegawa, 他10名
    • Organizer
      IEEE Nucl Sci Symposium
    • Place of Presentation
      Knoxville
    • Year and Date
      2010-11-02
    • Related Report
      2011 Final Research Report
  • [Presentation] Examination of a standardization method for 22Na sealed point sources under several measurement conditions2010

    • Author(s)
      Y.Sato, et al.
    • Organizer
      IEEE Nuclear Science Symposium
    • Place of Presentation
      Knoxville, TN
    • Year and Date
      2010-11-02
    • Related Report
      2010 Annual Research Report
  • [Presentation] 医学物理の第一線より2010

    • Author(s)
      長谷川智之
    • Organizer
      日本医学物理学会第100回学術大会
    • Place of Presentation
      学術総合センター(東京)
    • Year and Date
      2010-09-25
    • Related Report
      2010 Annual Research Report
  • [Presentation] 点状線源を用いたPET装置の定量性評価・校正法の開発:進捗状況報告2010

    • Author(s)
      長谷川智之, 他9名
    • Organizer
      第99回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-11
    • Related Report
      2011 Final Research Report
  • [Presentation] PET装置校正用点線源の線源校正における検出器-線源線源間距離の影響2010

    • Author(s)
      佐藤泰、長谷川智之, 他8名
    • Organizer
      第99回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2010-04-11
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源を用いたPET装置の定量性評価・校正法の開発:進捗状況報告2010

    • Author(s)
      長谷川智之, 他
    • Organizer
      日本医学物理学会第99回学術大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2010-04-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] PET装置校正用点線源の線源校正における検出器-線源線源間距離の影響2010

    • Author(s)
      佐藤泰, 他
    • Organizer
      日本医学物理学会第99回学術大会
    • Place of Presentation
      パシフィコ横浜(横浜)
    • Year and Date
      2010-04-11
    • Related Report
      2010 Annual Research Report
  • [Presentation] New calibration method using point-like radioactive sources for PET scanners2010

    • Author(s)
      T.Hasegawa, et al.
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Knoxville, TN
    • Year and Date
      2010-01-15
    • Related Report
      2010 Annual Research Report
  • [Presentation] Evaluation and Calibration of PET scanners with a Specially Designed Point-like Radioactive Source2009

    • Author(s)
      T.Hasegawa, 他9名
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Florida, USA
    • Year and Date
      2009-11-01
    • Related Report
      2009 Annual Research Report
  • [Presentation] Evaluation and Calibration of PET scanners with a Specially Designed Point-like Radioactive Source2009

    • Author(s)
      T. Hasegawa, 他9名
    • Organizer
      IEEE Medical Imaging Conference
    • Place of Presentation
      Flolida, USA
    • Year and Date
      2009-10-29
    • Related Report
      2011 Final Research Report
  • [Presentation] 感度・定量性評価のための微小球形状線源2009

    • Author(s)
      長谷川智之, 他9名
    • Organizer
      第49回日本核医学会
    • Place of Presentation
      旭川市
    • Year and Date
      2009-10-02
    • Related Report
      2009 Annual Research Report
  • [Presentation] PET装置校正用点線源の線源校正における線源の大きさの影響2009

    • Author(s)
      佐藤泰、長谷川智之, 他8名
    • Organizer
      第98回日本医学物理学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源を用いたPET装置の定量性評価校正法の開発:進捗状況報告2009

    • Author(s)
      長谷川智之, 他7名
    • Organizer
      第98回日本医学物理学会学術大会
    • Place of Presentation
      京都
    • Year and Date
      2009-09-19
    • Related Report
      2011 Final Research Report
  • [Presentation] 点状線源を用いたPET装置の定量性評価校正法の開発:進捗状況報告2009

    • Author(s)
      長谷川智之, 他7名
    • Organizer
      第98回日本医学物理学会学術大会
    • Place of Presentation
      京都市
    • Year and Date
      2009-09-18
    • Related Report
      2009 Annual Research Report
  • [Presentation] Monte Carlo simulation of standardization of^<22> Na using multi channel scintillation detectors2009

    • Author(s)
      Y. Sato, T. Hasegawa, 他6名
    • Organizer
      17th International Conference on Radionuclide Metrology and its Applications
    • Place of Presentation
      Bratislava, Slovakia
    • Year and Date
      2009-09-07
    • Related Report
      2011 Final Research Report
  • [Presentation] マルチチャンネルシンチレーション検出器を用いた密封^<22> Na小線源の放射能絶対測定2009

    • Author(s)
      佐藤泰、長谷川智之, 他5名
    • Organizer
      第46回アイソトープ放射線研究発表会
    • Year and Date
      2009-07-01
    • Related Report
      2011 Final Research Report
  • [Presentation] 水等価シンチレータによる陽電子の空間的な広がりの観測2009

    • Author(s)
      長谷川智之, 他3名
    • Organizer
      第97回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Year and Date
      2009-04-17
    • Related Report
      2011 Final Research Report
  • [Presentation] 感度・定量性評価のための微小球形状線源2009

    • Author(s)
      長谷川智之, 他9名
    • Organizer
      第49回日本核医学会
    • Place of Presentation
      旭川
    • Related Report
      2011 Final Research Report
  • [Presentation] 微小球形状線源のモンテカルロ・シミュレーションによる基本的物理特性評価2009

    • Author(s)
      長谷川智之, 他8名
    • Organizer
      第97回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report
  • [Presentation] 円筒多重カプセルタイプの点状線源によるPET装置の絶対校正・評価法2009

    • Author(s)
      長谷川智之, 他8名
    • Organizer
      第97回日本医学物理学会学術大会
    • Place of Presentation
      横浜
    • Related Report
      2011 Final Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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