Analysis of microstructure in brain activation area
| Project/Area Number |
21613001
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Non-invasive neuroimaging
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| Research Institution | Hokkaido University |
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Principal Investigator |
YAMAMOTO Toru 北海道大学, 大学院・保健科学研究院, 教授 (80261361)
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| Co-Investigator(Kenkyū-buntansha) |
KIDA Ikuhiro 情報通信研究機構, 脳情報通信融合研究センター, 主任研究員 (60374716)
THA Khin khin 北海道大学, 大学院・医学研究科, 特任助教 (20451445)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥4,680,000 (Direct Cost: ¥3,600,000、Indirect Cost: ¥1,080,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2009: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
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| Keywords | MRI / 血行動態 / 微小循環 / 脳機能 / fMRI |
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| Research Abstract |
We performed the same fMRI(functional Magnetic Resonance Imaging) study for different head positions by tilting the volunteer's head and showed that the activation area is strongly influenced by the orientation of the draining vein from the activation focus where the neurons are activated. And we showed that the MR signal from the cortex capillary bed contains signal from interstitial fluid which may depend on oxygen concentration in tissue, and that the sum of the BOLD(Blood oxygenation level-dependent) signals from the activation focus correlates quantitatively with the sum of the peak-to-peak amplitude of the evoked potential responses.
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Report
(4 results)
Research Products
(36 results)
