| Budget Amount *help |
¥3,340,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,600,000 (Direct Cost: ¥1,600,000)
Fiscal Year 2009: ¥700,000 (Direct Cost: ¥700,000)
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| Research Abstract |
Adult neurogenesis takes place in specific regions of the mammalian brain such as the subventricular zone in the forebrain and the dentate gyrus in the hippocampus. I found that neuron production in the dentate gyrus shows a day/night variation throughout the day. The daily variation is controlled by the circadian clock. Importantly, suppression of the neuron production causes altered mood of mice, implicating the time-of-day-dependent regulation of neuron production is important for mood stabilization.
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