Investigation and application of new metabolic pathways involved in the synthesis of inosinate and guanylate
| Project/Area Number |
21650193
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Eating habits, studies on eating habits
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| Research Institution | Kobe Shoin Women's University |
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Principal Investigator |
SHIMIZU Riko (KATAHIRA Riko) 神戸松蔭女子学院大学, 人間科学部, 准教授 (70204427)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,350,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2009: ¥1,900,000 (Direct Cost: ¥1,900,000)
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| Keywords | うまみ / ヌクレオチド / 代謝経路 / 加工 / 調理 / 植物性食品 / 動物性食品 |
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| Research Abstract |
New metabolic pathways involved in the synthesis of inosinate and guanylate were investigated. Shiitake mushrooms(Lentinula edodes), cultured Japanese jack mackerel(Trachurus japonicus) and Japanese radish(Raphanus sativus) were chosen as the representatives of mushrooms, fishes and vegetables, respectively. Metabolic profiles of purine ribonucleotides in these foods were examined based on the in situ metabolic fate of radio-labelled precursors and the in vitro activities of enzymes. Inosinate and guanylate were synthesized via salvage pathways in all foods. It was suggested that salvage pathways were operative in these foods under certain conditions of cooking, processing and preservation.
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Report
(4 results)
Research Products
(2 results)
