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Investigation and application of new metabolic pathways involved in the synthesis of inosinate and guanylate

Research Project

Project/Area Number 21650193
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Eating habits, studies on eating habits
Research InstitutionKobe Shoin Women's University

Principal Investigator

SHIMIZU Riko (KATAHIRA Riko)  神戸松蔭女子学院大学, 人間科学部, 准教授 (70204427)

Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,350,000 (Direct Cost: ¥3,200,000、Indirect Cost: ¥150,000)
Fiscal Year 2011: ¥650,000 (Direct Cost: ¥500,000、Indirect Cost: ¥150,000)
Fiscal Year 2010: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2009: ¥1,900,000 (Direct Cost: ¥1,900,000)
Keywordsうまみ / ヌクレオチド / 代謝経路 / 加工 / 調理 / 植物性食品 / 動物性食品
Research Abstract

New metabolic pathways involved in the synthesis of inosinate and guanylate were investigated. Shiitake mushrooms(Lentinula edodes), cultured Japanese jack mackerel(Trachurus japonicus) and Japanese radish(Raphanus sativus) were chosen as the representatives of mushrooms, fishes and vegetables, respectively. Metabolic profiles of purine ribonucleotides in these foods were examined based on the in situ metabolic fate of radio-labelled precursors and the in vitro activities of enzymes. Inosinate and guanylate were synthesized via salvage pathways in all foods. It was suggested that salvage pathways were operative in these foods under certain conditions of cooking, processing and preservation.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (2 results)

All 2012

All Presentation (2 results)

  • [Presentation] シイタケ(Lentinula edodes)のグアニル酸生成に関与する代謝経路2012

    • Author(s)
      片平理子
    • Organizer
      日本家政学会第64回大会
    • Year and Date
      2012-05-13
    • Related Report
      2011 Final Research Report
  • [Presentation] シイタケ(Lentinula edodes)のグアニル酸生成に関与する代謝経路2012

    • Author(s)
      片平理子(清水理子)
    • Organizer
      日本家政学会
    • Place of Presentation
      大阪市立大学(大阪)
    • Year and Date
      2012-05-12
    • Related Report
      2011 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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