| Project/Area Number |
21651055
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Nanomaterials/Nanobioscience
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,010,000 (Direct Cost: ¥2,800,000、Indirect Cost: ¥210,000)
Fiscal Year 2011: ¥910,000 (Direct Cost: ¥700,000、Indirect Cost: ¥210,000)
Fiscal Year 2010: ¥600,000 (Direct Cost: ¥600,000)
Fiscal Year 2009: ¥1,500,000 (Direct Cost: ¥1,500,000)
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| Keywords | 超常磁性鉄酸化物 / SPION / ナノパーティクル / ドラッグデリバリーシステム / DDS / 反応の磁場制御 / 生体イメージング / 磁性 / 蛍光 / パラジウム / 反応速度 / 反応 / 磁場 |
|---|
| Research Abstract |
In order to control chemical reactions under magnetic field by using of super-paramagnetic iron oxide nanoparticles(SPIONs), Carrier SPIONs introduced with functional molecules and Catalyst SPIONs attached with Pd complex to disconnect the functional molecules from the Carrier SPIONs were prepared, and their reactivity under magnetic and non-magnetic fields was investigated. A significant differece of reaction rate between magnetic and non-magnetic cconditions has not been observed, but release reaction of functional molecules was observed even under non-magnetic conditions. This type of reaction is promising to be applied for DDS, bio-imaging and so on.
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