| Budget Amount *help |
¥3,340,000 (Direct Cost: ¥3,100,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥1,500,000 (Direct Cost: ¥1,500,000)
Fiscal Year 2009: ¥800,000 (Direct Cost: ¥800,000)
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| Research Abstract |
In invertebrate, a comparative analysis of larval and adult innate immune system, from a perspective of ontology, has not been made. We revealed that the allorecognition capability of immune cells is acquired after metamorphosis in the immune system of the starfish, Asterina pectinifera. Although a global analysis comparing genes expression in the larval and the adult immune cells showed that the majority of immune-related gene is common to both cell types, a certain type of gene that suggests the alteration of immune recognition system was present in these common genes.
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