| Project/Area Number |
21659069
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
General medical chemistry
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| Research Institution | The University of Tokyo |
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Principal Investigator |
NAGAMURA Tokiko (INOUE Tokiko) 東京大学, 医科学研究所, 講師 (70240736)
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| Co-Investigator(Renkei-kenkyūsha) |
ISHIGE Ikuo 東京大学, 医科学研究所, 特任研究員 (30396957)
KOBAYASHI Seiichiro 東京大学, 医科学研究所, 助教 (70376622)
NAGAMURA Fumitaka 東京大学, 医科学研究所, 教授 (90282491)
OOI Jun 東京大学, 医科学研究所, 助教 (20302606)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,270,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2009: ¥1,100,000 (Direct Cost: ¥1,100,000)
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| Keywords | 再生医療 / 臍帯 / 組織幹細胞 / ES細胞 / CD34陽性細胞 / 間葉系幹細胞 / VSEL / 臍帯血 |
|---|
| Research Abstract |
This study is aimed to find the source cells for regenerative medicine, such as Very Small ES like(VSEL) cells in umbilical cord blood(UCB). We found the SSEA3^+very small N/C high-ratio cells, but too low incidence to do further analysis. On the other hand, in umbilical cord(UC)-derived mesenchymal stem cells(MSCs), we found the SSEA3/4+cells with ES-specific gene markers. Not only UCB, but also UC-MSCs may be good candidate source for the regenerative medicine.
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