• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

Construction of the experimental system about the immunity influence of an indoor disposition

Research Project

Project/Area Number 21659161
Research Category

Grant-in-Aid for Challenging Exploratory Research

Allocation TypeSingle-year Grants
Research Field Hygiene
Research InstitutionKawasaki Medical School

Principal Investigator

OTSUKI Takemi  川崎医科大学, 医学部, 教授 (40160551)

Co-Investigator(Kenkyū-buntansha) NISHIMURA Yasumitsu  川崎医科大学, 医学部, 准教授 (90360271)
TAKEI Naoko  川崎医科大学, 医学部, 助教 (00509276)
MATSUZAKI Hidenori  川崎医科大学, 医学部, 助教 (80335463)
LEE Suni  川崎医科大学, 医学部, 助教 (70414026)
MAEDA Megumi  川崎医科大学, 医学部, 助教 (20434988)
Project Period (FY) 2009 – 2011
Project Status Completed (Fiscal Year 2011)
Budget Amount *help
¥3,270,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2009: ¥1,200,000 (Direct Cost: ¥1,200,000)
Keywordsマイナス荷電粒子 / 室内気質 / 免疫 / T細胞 / NK細胞 / 活性化 / サイトカイン / 長期モニター / NK活性 / T細胞機能
Research Abstract

Result to build a negatively charged particle indoor air quality advantage, stay for 2.5 hours by healthy volunteers, have been type tested and only at night for two weeks, and minor but significant increase in interleukin-2 short-term, so had observed enhanced activity of natural killer cells in the(2 weeks) period during this time, and the experimental building of that system, the result was verified, the degree of dominance of the charged particle is negative, the order experimentally were different, experimentally, it was found that this environment to induce the activation of natural killer cell helper T cell activation.

Report

(4 results)
  • 2011 Annual Research Report   Final Research Report ( PDF )
  • 2010 Annual Research Report
  • 2009 Annual Research Report
  • Research Products

    (18 results)

All 2011 2010 2009

All Journal Article (8 results) (of which Peer Reviewed: 6 results) Presentation (9 results) Book (1 results)

  • [Journal Article] 森林環境要素の免疫機能に及ぼす効果2011

    • Author(s)
      大槻剛巳
    • Journal Title

      森林セラピー

      Volume: Np. 5 Pages: 6-6

    • Related Report
      2011 Final Research Report
  • [Journal Article] Two weeks of permanence in negatively-charged air conditions causes alteration of natural killer cell function2009

    • Author(s)
      Takahashi K, Otsuki T, Mase A, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Shirahama T, Miura Y, Morimoto K.
    • Journal Title

      Int J Immunopathol Pharmacol

      Volume: 22(2) Pages: 333-342

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] The biological effects of negatively-charged indoor aire conditions2009

    • Author(s)
      Otsuki T, Takahashi K, Mase A, Kawado T, Kotani M, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Nishimura Y, Miura Y, Shirahama T, Yoshimatsu M, Morimoto K.
    • Journal Title

      Kawasaki Med J

      Volume: 35(3) Pages: 205-214

    • NAID

      110007338961

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] マイナス荷電粒子優位な室内空気環境の生体影響の観察-精神・神経・内分泌・免疫ネットワークへの影響について-2009

    • Author(s)
      西村泰光, 高橋一聡, 間瀬昭則, 河戸隆, 小谷宗男, 阿見和久, 松島弘樹, 白濱毅, 吉松道晴, 前田恵, 村上周子, 林宏明, 熊谷直子, 陳〓, 三浦由恵, 森本兼曩, 大槻剛巳
    • Journal Title

      日本職業・環境アレルギー学会雑誌

      Volume: 16(2) Pages: 15-24

    • NAID

      40016794942

    • Related Report
      2011 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two weeks of abidance in negatively-charged air conditions causes alteration of natural killer cell function2009

    • Author(s)
      Takahashi K, et al
    • Journal Title

      Int J Immunopathol Pharmacol 22

      Pages: 333-342

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] The biological effects of negatively-charged indoor sire conditions2009

    • Author(s)
      Otsuki T, et al
    • Journal Title

      Kawasaki Med J 35

      Pages: 205-214

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] マイナス荷電粒子優位な室内空気環境の生体影響の観察 -精神・神経・内分泌・免疫ネットワークへの影響について-2009

    • Author(s)
      西村泰光, 他
    • Journal Title

      日本職業・環境アレルギー学会雑誌 16

      Pages: 15-24

    • NAID

      40016794942

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Establishment of Negatively-charged Indoor Air Conditions and their Biological Effects2009

    • Author(s)
      Otsuki T, Takahashi K, Mase A, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chne Y, Miura Y, Shirahama T, Yoshimatsu M, Morimoto K.
    • Journal Title

      In Buildings and the Environment. Authors/Editors : Jonas Nemecek and Patrik Schulz. Pub.Date : 2009 4th Quarter ISBN : 978-1-60876-128-9(C)2009 Nova Science Publishers, Inc. 2009

      Pages: 201-214

    • Related Report
      2009 Annual Research Report
  • [Presentation] 室内空気質による健康増進への取組に関する基礎的研究2011

    • Author(s)
      大槻剛巳
    • Organizer
      第2回川崎医科大学学術集会
    • Place of Presentation
      川崎医科大学現代医学教育博物館
    • Year and Date
      2011-08-06
    • Related Report
      2011 Final Research Report
  • [Presentation] 室内空気質による健康増進への取組に関する基礎的研究2011

    • Author(s)
      大槻剛巳
    • Organizer
      第2回川崎医科大学学術集会
    • Place of Presentation
      川崎医科大学現代医学教育博物館(岡山県)
    • Year and Date
      2011-08-06
    • Related Report
      2011 Annual Research Report
  • [Presentation] 健康増進住宅への試み2011

    • Author(s)
      大槻剛巳
    • Organizer
      第39回メディカルテクノおかやまサロン
    • Place of Presentation
      岡山大学鹿田キャンパス総合教育研究棟1階
    • Year and Date
      2011-04-25
    • Related Report
      2011 Final Research Report
  • [Presentation] マイナス荷電粒子優位な室内環境の免疫影響2011

    • Author(s)
      大槻剛巳, 高橋一聡, 真鍋弘穀, 小谷宗男, 前田恵, 熊谷直子, 松崎秀紀, 李順姫, 西村泰光
    • Organizer
      第18回日本免疫毒性学会
    • Place of Presentation
      千葉大学けやき会館(千葉県)
    • Related Report
      2011 Annual Research Report
  • [Presentation] マイナス荷電粒子優位の室内空気環境と精神・神経・内分泌・免疫ネットワーク応答の解析-in vitro実験系の試み-2010

    • Author(s)
      大槻剛巳, 西村泰光, 前田恵, 熊谷直子, 林宏明
    • Organizer
      第1回川崎医科大学学術集会
    • Place of Presentation
      川崎医科大学校舎棟M702/教職員ラウンジ
    • Year and Date
      2010-08-07
    • Related Report
      2011 Final Research Report
  • [Presentation] 住居環境と健康2010

    • Author(s)
      大槻剛巳
    • Organizer
      おかやま生体信号研究会第3回例会.
    • Place of Presentation
      川崎医療福祉大学講義棟4603講義室
    • Year and Date
      2010-05-31
    • Related Report
      2010 Annual Research Report
  • [Presentation] 環境と生体反応:健康被害から健康増進へ2009

    • Author(s)
      大槻剛巳
    • Organizer
      岡山県医用工学研究会平成21年度第1回セミナー
    • Place of Presentation
      岡山大学鹿田キャンパス附属図書館3階情報実習室
    • Year and Date
      2009-06-18
    • Related Report
      2011 Final Research Report 2009 Annual Research Report
  • [Presentation] マイナス荷電空気環境による効果2009

    • Author(s)
      大槻剛巳, 西村泰光, 森本兼曩
    • Organizer
      第79回日本衛生学会総会「森林の健康影響メカニズムをさぐる」森林医学研究会
    • Place of Presentation
      北里大学白金キャンパス
    • Year and Date
      2009-03-30
    • Related Report
      2011 Final Research Report
  • [Presentation] マイナス荷電空気環境による効果2009

    • Author(s)
      大槻剛巳, 他
    • Organizer
      第79回日本衛生学会総会.「森林の健康影響メカニズムをさぐる」森林医学研究会
    • Place of Presentation
      北里大学白金キャンパス
    • Year and Date
      2009-03-30
    • Related Report
      2009 Annual Research Report
  • [Book] Establishment of Negatively-charged Indoor Air Conditions and their Biological Effects. In Buildings and the Environment. Authors/Editors : Jonas Nemecek and Patrik Schulz2009

    • Author(s)
      Otsuki T, Takahashi K, Mase A, Kawado T, Kotani M, Nishimura Y, Maeda M, Murakami S, Kumagai N, Hayashi H, Chen Y, Miura Y, Shirahama T, Yoshimatsu M, Morimoto K.
    • Publisher
      Nova Science Publishers
    • Related Report
      2011 Final Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi