Budget Amount *help |
¥3,300,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2011: ¥1,300,000 (Direct Cost: ¥1,000,000、Indirect Cost: ¥300,000)
Fiscal Year 2010: ¥1,000,000 (Direct Cost: ¥1,000,000)
Fiscal Year 2009: ¥1,000,000 (Direct Cost: ¥1,000,000)
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Research Abstract |
Modern society needs keys to cope with stress-related disorders of which irritable bowel syndrome(IBS)is representative one. The purpose of this study is clarify the pathophysiology of gene-environment interaction including psychosocial factors, gut microbiota, and biomarkers in IBS. Results indicated distinct abnormalities in gut microbiota and their products, consistent effects of stress, some cytokines, and susceptible genes including serotonin-related genes. Further studies on gene-environment interaction in this issue are warranted
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