Induction of differentiation from iPS cells to bronchioalveolar stem cells
| Project/Area Number |
21659207
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Tohoku University |
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Principal Investigator |
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥2,540,000 (Direct Cost: ¥2,300,000、Indirect Cost: ¥240,000)
Fiscal Year 2011: ¥1,040,000 (Direct Cost: ¥800,000、Indirect Cost: ¥240,000)
Fiscal Year 2010: ¥800,000 (Direct Cost: ¥800,000)
Fiscal Year 2009: ¥700,000 (Direct Cost: ¥700,000)
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| Keywords | 閉塞性肺疾患 / 誘導多能性幹細胞 / 気管支肺胞上皮幹細胞 / 細胞・組織 / 発生・分化 |
|---|
| Research Abstract |
It is difficult to adopt the regenerative procedures to respiratory medicine for the anatomic complexity. However, regenerative procedures should be considered in respiratory medicine, which includes clinical states with irreversible tissue damage. In this research proposal, we have developed basic technologies that are demanded for induction of differentiation from iPS cells to bronchioalveolar stem cells.
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Report
(4 results)
Research Products
(109 results)
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[Journal Article] Usefulness of linezolid in the treatment of hospital-acquired pneumonia caused by MRSA : a prospective observational study2012
Author(s)
Watanabe A, Goto H, Soma K, Kikuchi T, Gomi K, Miki H, Maemondo M, Ikeda H, Kuroki J, Wada H, Yokoyama T, Izumi S, Mitsutake K, Ueda Y
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Journal Title
J Infect Chemother
Volume: (in press)
Related Report
Peer Reviewed
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[Journal Article] Runx1-deficiency in CD4+ T cells causes fatal autoimmune inflammatory lung disease due to spontaneous hyperactivation of cells2012
Author(s)
Wong WF, Kohu K, Nakamura A, Ebina M, Kikuchi T, Tazawa R, Tanaka K, Kon S, Funaki T, Sugahara-Tobinai A, Looi CY, Endo S, Funayama R, Kurokawa M, Habu S, Ishii N, Fukumoto M, Nakata K, Takai T, Satake M
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Journal Title
J Immunol
Volume: (in press)
Related Report
Peer Reviewed
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[Journal Article] Runx1-deficie ncy in CD4+ T cells causes fatal autoimmune inflammatory lung disease due to spontaneous hyperactivation of cells2012
Author(s)
Wong WF, Kohu K, Nakamura A, Ebina M, Kikuchi T, Tazawa R, Tanaka K, Kon S, Funaki T, Sugahara-Tobinai A, Looi CY, Endo S, Funayama R, Kurokawa M, Habu S, Ishii N, Fukumoto M, Nakata K, Takai T, Satake M
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Journal Title
J Immunol
Volume: (未定)(印刷中)
Related Report
Peer Reviewed
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[Journal Article] Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells2011
Author(s)
Daito H, Kikuchi T, Sakakibara T, Gomi K, Damayanti T, Zaini J, Tode N, Kanehira M, Koyama S, Fujimura S, Ebina M, Ishii KJ, Akira S, Takai T, Watanabe A, Nukiwa T
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Journal Title
Eur Respir J
Volume: 38
Pages: 688-701
Related Report
Peer Reviewed
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[Journal Article] Regulation of adenosine 5'-triphosphate (ATP)-gated P2X(4)receptors on tracheal smooth muscle cells2009
Author(s)
Nagaoka M, Nara M, Tamada T, Kume H, Oguma T, Kikuchi T, Zaini J, Moriya T, Ichinose M, Tamura G, Hattori T
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Journal Title
Respir Physiol Neurobiol
Volume: 166
Pages: 61-7
Related Report
Peer Reviewed
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[Journal Article] Association between mycobacterial genotypes and disease progression in Mycobacterium avium pulmonary infection2009
Author(s)
Kikuchi T, Watanabe A, Gomi K, Sakakibara T, Nishimori K, Daito H, Fujimura S, Tazawa R, Inoue A, Ebina M, Tokue Y, Kaku M, Nukiwa T
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Journal Title
Thorax
Volume: 64
Pages: 901-7
Related Report
Peer Reviewed
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