| Project/Area Number |
21659219
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Neurology
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| Research Institution | The University of Tokyo |
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Principal Investigator |
IWATA Atsushi 東京大学, 医学部附属病院, 特任准教授 (40401038)
|
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| Co-Investigator(Kenkyū-buntansha) |
KOWA Hisatomo 神戸大学, 医学部附属病院, 准教授 (60396728)
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|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,290,000 (Direct Cost: ¥2,900,000、Indirect Cost: ¥390,000)
Fiscal Year 2011: ¥1,690,000 (Direct Cost: ¥1,300,000、Indirect Cost: ¥390,000)
Fiscal Year 2010: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2009: ¥700,000 (Direct Cost: ¥700,000)
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| Keywords | 神経分子病態学 / メタゲノミクス / パーキンソン病 / 腸内細菌 |
|---|
| Research Abstract |
As a cause of sporadic Parkinson's disease, we hypothesized that the gut microflora in patients might be compromised. We took 10 stool samples and extracted DNA from patients and compared with 10 control samples. DGGE analysis revealed three distinctive bands in the patient group, which was sequenced and identified. Further analysis of large number samples are needed to confirm the result.
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