Development of newly-designed molecular targeted diagnostic PET study using system A amino acid tracer
| Project/Area Number |
21659297
|
|---|
| Research Category |
Grant-in-Aid for Challenging Exploratory Research
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Radiation science
|
|---|
| Research Institution | Research Institute, Shiga Medical Center |
|---|
Principal Investigator |
HIGASHI Tatsuya 滋賀県立成人病センター(研究所), 画像研究部門, 総括研究員 (50324629)
|
|---|
| Co-Investigator(Kenkyū-buntansha) |
NISHII Ryuichi 宮崎大学, 医学部, 講師 (60463212)
KAGAWA Shinya 滋賀県立成人病センター(研究所), 画像研究部門, 主任研究員 (10393191)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥3,270,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥270,000)
Fiscal Year 2011: ¥1,170,000 (Direct Cost: ¥900,000、Indirect Cost: ¥270,000)
Fiscal Year 2010: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2009: ¥1,200,000 (Direct Cost: ¥1,200,000)
|
|---|
| Keywords | アミノ酸輸送システム / PET検査 / 脳腫瘍 / 胸部腫瘍 / 前立腺腫瘍 |
|---|
| Research Abstract |
In order to overcome the drawback of false positive diagnosis at FDG-PET in the patients with inflammatory diseases, we have developed[N-methyl-^<11> C] MeAIB, an artificial system A amino acid PET tracer, confirmed its safety at animal and human study, established its sophisticated synthesis methods, and established its basic procedure at clinical oncologic human study. We have finished more than 200 cases of patients with various tumors including brain tumors, chest cancers, and prostate cancers, and MeAIB-PET has shown its valuable clinical role in the differential diagnosis between cancers and inflammatory diseases.
|
Report
(4 results)
Research Products
(25 results)
