| Project/Area Number |
21659466
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| Research Category |
Grant-in-Aid for Challenging Exploratory Research
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| Allocation Type | Single-year Grants |
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| Research Field |
Surgical dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
SAKAI Takayoshi 大阪大学, 大学院・歯学研究科, 教授 (90379082)
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| Co-Investigator(Kenkyū-buntansha) |
NOHARA Kanji 大阪大学, 歯学部附属病院, 助教 (20346167)
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| Project Period (FY) |
2009 – 2011
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| Project Status |
Completed (Fiscal Year 2011)
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| Budget Amount *help |
¥3,360,000 (Direct Cost: ¥3,000,000、Indirect Cost: ¥360,000)
Fiscal Year 2011: ¥1,560,000 (Direct Cost: ¥1,200,000、Indirect Cost: ¥360,000)
Fiscal Year 2010: ¥900,000 (Direct Cost: ¥900,000)
Fiscal Year 2009: ¥900,000 (Direct Cost: ¥900,000)
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| Keywords | 唇顎口蓋裂 / 口蓋閉鎖 / 遺伝子発現 / 口蓋裂 / 遺伝子 / プロファイル / マイクロアレー / 臓器 / 再生 / 唾液腺 / 分枝 / 形態形成 / 口腔乾燥症 |
|---|
| Research Abstract |
The aim of this research is to clarify the molecular mechanism of palatal fusion for clinical treatment of cleft palate. Gene expression profile of palatal processes before, during and after fusion was established, and some of genes that could be related to palatal fusion were identified.
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