| Budget Amount *help |
¥24,700,000 (Direct Cost: ¥19,000,000、Indirect Cost: ¥5,700,000)
Fiscal Year 2011: ¥6,760,000 (Direct Cost: ¥5,200,000、Indirect Cost: ¥1,560,000)
Fiscal Year 2010: ¥6,630,000 (Direct Cost: ¥5,100,000、Indirect Cost: ¥1,530,000)
Fiscal Year 2009: ¥11,310,000 (Direct Cost: ¥8,700,000、Indirect Cost: ¥2,610,000)
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| Research Abstract |
Depending on molecular environment, some photo-functional proteins(human visual cone pigments and fluorescent proteins) significantly change their photo-absorption/emission energy. We performed quantum chemical calculations to analyze the mechanism. We found that, upon excitation, the charge distributions of the chromophores change significantly and the proteins produce polarized electrostatic potential. These two facts cause a synergy effect on the excitation energy. We also found that the wave functions of amino acids close to the chromophore also affect the excitation energy in some retinal proteins. To analyze the electronic effect of the protein environment, we have developed a new localization scheme that can localize MOs into predefined shapes and regions. This localization scheme was applied to analyze the pathway for the excitation transfer.
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