Development of fusion molecular imaging technique based on functional molecular design
| Project/Area Number |
21685019
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Chemistry related to living body
|
|---|
| Research Institution | Osaka University |
|---|
Principal Investigator |
MIZUKAMI Shin 大阪大学, 大学院・工学研究科, 准教授 (30420433)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥27,170,000 (Direct Cost: ¥20,900,000、Indirect Cost: ¥6,270,000)
Fiscal Year 2011: ¥6,890,000 (Direct Cost: ¥5,300,000、Indirect Cost: ¥1,590,000)
Fiscal Year 2010: ¥9,620,000 (Direct Cost: ¥7,400,000、Indirect Cost: ¥2,220,000)
Fiscal Year 2009: ¥10,660,000 (Direct Cost: ¥8,200,000、Indirect Cost: ¥2,460,000)
|
|---|
| Keywords | 蛍光プローブ / MRI / ラベル化 / イメージング / β-ラクタマーゼ / βラクタマーゼ / タンパク質ラベル / 量子ドット |
|---|
| Research Abstract |
Several elemental technologies for next-generation molecular imaging methods were developed by integrating chemical principle-based functional probe design, protein engineering, and latest instrumental analyses. Specifically, three technologies, which are^19F MRI detection system to visualize living cellular gene expression, novel protein labeling technology, and time-resolved photoluminescence imaging technology for proteins, were developed.
|
Report
(4 results)
Research Products
(90 results)
