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Accurate Measurement of Arterial Dynamics by High Frame Rate Ultrasonic Imaging

Research Project

Project/Area Number 21686036
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Measurement engineering
Research InstitutionTohoku University

Principal Investigator

HASEGAWA Hideyuki  東北大学, 大学院・医工学研究科, 准教授 (00344698)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥5,460,000 (Direct Cost: ¥4,200,000、Indirect Cost: ¥1,260,000)
Fiscal Year 2010: ¥2,600,000 (Direct Cost: ¥2,000,000、Indirect Cost: ¥600,000)
Fiscal Year 2009: ¥2,860,000 (Direct Cost: ¥2,200,000、Indirect Cost: ¥660,000)
Keywords動脈壁2次元変位 / 微小ひずみ / 血流 / 血管動態 / 超音波
Research Abstract

The rupture of atherosclerotic plaque leads to serious events, such as cerebral infarction and stroke. Therefore, it is important to assess the arterial dynamics to evaluate the vulnerability of plaque. In this study, methods for measurement of the arterial dynamics, such as accurate measurement of 2-dimensional motion of the arterial wall and a new method for imaging blood flow at a very high frame rate of 3500 Hz, have been developed.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (46 results)

All 2011 2010 2009

All Journal Article (22 results) (of which Peer Reviewed: 22 results) Presentation (22 results) Book (2 results)

  • [Journal Article] σ1-Receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice2010

    • Author(s)
      Hideaki Tagashira, Shenuarin Bhuiyan, Norifumi Shioda, Hideyuki Hasegawa, Hiroshi Kanai, and Kohji Fukunaga
    • Journal Title

      American Journal of Physiology Heart and Circulatory Physiology

      Volume: 299巻 Pages: 1535-1545

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Two-Dimensional Tracking of Heart Wall for Detailed Analysis of Heart Function at High Temporal and Spatial Resolutions2010

    • Author(s)
      Yasunori Honjo, Hideyuki Hasegawa, and Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 49巻

    • NAID

      210000068928

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Line-Focus Array Transducers for Effective Actuation of Tissue2010

    • Author(s)
      Tomotaka Sawada, Hideyuki Hasegawa, and Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 49巻

    • NAID

      210000068924

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] σ1-Receptor stimulation with fluvoxamine ameliorates transverse aortic constriction-induced myocardial hypertrophy and dysfunction in mice2010

    • Author(s)
      Hideaki Tagashira, Shenuarin Bhuiyan, Norifumi Shioda, Hideyuki Hasegawa, Hiroshi Kanai, Kohji Fukunaga
    • Journal Title

      American Journal of Physiology Heart and Circulatory Physiology

      Volume: 299 Pages: 1535-1545

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Two-Dimensional Tracking of Heart Wall for Detailed Analysis of Heart Function at High Temporal and Spatial Resolutions2010

    • Author(s)
      Yasunori Honjo, Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 49

    • NAID

      210000068928

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Line-Focus Array Transducers for Effective Actuation of Tissue2010

    • Author(s)
      Tomotaka Sawada, Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 49

    • NAID

      210000068924

    • Related Report
      2010 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Phase-Sensitive Lateral Motion Estimator for Measurement of Artery-Wall Displacement-Phantom Study2009

    • Author(s)
      Hideyuki Hasegawa and Hiroshi Kanai
    • Journal Title

      IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control

      Volume: 56巻 Pages: 2450-2462

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of Lifestyle-Related Diseases on Carotid Arterial Wall Elasticity as Evaluated by an Ultrasonic Phased-Tracking Method in Japanese Subjects2009

    • Author(s)
      Toshio Yamagishi , Makoto Kato, Yoshiro Koiwa, Hideyuki Hasegawa and Hiroshi Kanai
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 16巻 Pages: 782-791

    • NAID

      10026144266

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] 超音波RF信号のコヒーレンスに基づく心臓壁領域同定2009

    • Author(s)
      高橋 広樹, 長谷川英之, 金井 浩
    • Journal Title

      超音波医学

      Volume: 36巻 Pages: 679-681

    • NAID

      10026312212

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Carotid Arterial Elasticity is a Sensitive Atherosclerosis Value Reflecting Visceral Fat Accumulation in Obese subjects2009

    • Author(s)
      Ai Tokita, Yasushi Ishigaki, Hisashi Okimoto, Hideyuki Hasegawa, Yoshiro Koiwa, Makoto Kato, Hisamitsu Ishihara, Yoshinori Hinokio, Hideki Katagiri, Hiroshi Kanai, Yoshitomo Oka
    • Journal Title

      Atherosclerosis

      Volume: 206巻 Pages: 168-172

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Plaque Stabilization by Fluvastatin with Carotid Intima-Medial Elasticity Measured by a Transcutaneous Ultrasonic-Based Tissue Characterization System2009

    • Author(s)
      Toshio Yamagishi, Makoto Kato, Yoshiro Koiwa, Ken Omata, Hideyuki Hasegawa and Hiroshi Kanai
    • Journal Title

      Journal of Atherosclerosis and Thrombosis

      Volume: 16巻 Pages: 662-673

    • NAID

      10026143796

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between upper limb peripheral artery stiffness using the radial artery and atherosclerotic parameters2009

    • Author(s)
      Shuumarjav Uurtuya, Kazuhiko Kotani, Nobuyuki Taniguchi, Hiroaki Matsunaga, Hiroshi Kanai, Hideyuki Hasegawa, Kazuomi Kario, Shun Ishibashi, and Kouichi Itoh
    • Journal Title

      Journal of Medical Ultrasonics

      Volume: 36巻 Pages: 129-135

    • NAID

      10025328146

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Flow-Mediated Change in Viscoelastic Property of Radial Arterial Wall Measured by 22MHz Ultrasound2009

    • Author(s)
      Kazuki Ikeshita, Hideyuki Hasegawa, and Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 48巻

    • NAID

      210000067151

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Estimation of Scatterer Diameter Using Ultrasonic Backscattering Property for Assessment of Red Blood Cell Aggregation2009

    • Author(s)
      Nobutaka Saitoh, Hideyuki Hasegawa, and Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics

      Volume: 48巻

    • NAID

      210000067149

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Phase-Sensitive Lateral Motion Estimator for Measurement of Artery-Wall Displacement-Phantom Study2009

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 56

      Pages: 2450-2462

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Estimation of Scatterer Diameter Using Ultrasonic Backscattering Property for Assessment of Red Blood Cell Aggregation2009

    • Author(s)
      Nobutaka Saitoh, Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics 48

    • NAID

      210000067149

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Flow-Mediated Change in Viscoelastic Property of Radial Arterial Wall Measured by 22MHz Ultrasound2009

    • Author(s)
      Kazuki Ikeshita, Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      Japanese Journal of Applied Physics 48

    • NAID

      210000067151

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Relationship between upper limb peripheral artery stiffness using the radial artery and atherosclerotic parameters2009

    • Author(s)
      Shuumarjav Uurtuya, Kazuhiko Kotani, Nobuyuki Taniguchi, Hiroaki Matsunaga, Hiroshi Kanai, Hideyuki Hasegawa, Kazuomi Kario, Shun Ishibashi, Kouichi Itoh
    • Journal Title

      Journal of Medical Ultrasonics 36

      Pages: 129-135

    • NAID

      10025328146

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Evaluation of Plaque Stabilization by Fluvastatin with Carotid Intima-Medial Elasticity Measured by a Transcutaneous Ultrasonic-Based Tissue Characterization System2009

    • Author(s)
      Toshio Yamagishi, Makoto Kato, Yoshiro Koiwa, Ken Omata, Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      Journal of Atherosclerosis and Thrombosis 16

      Pages: 662-673

    • NAID

      10026143796

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Carotid Arterial Elasticity is a Sensitive Atherosclerosis Value Reflecting Visceral Fat Accumulation in Obese subjects2009

    • Author(s)
      Ai Tokita, Yasushi Ishigaki, Hisashi Okimoto, Hideyuki Hasegawa, Yoshiro Koiwa, Makoto Kato, Hisamitsu Ishihara, Yoshinori Hinokio, Hideki Katagiri, Hiroshi Kanai, Yoshitomo Oka
    • Journal Title

      Atherosclerosis 206

      Pages: 168-172

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] 超音波RF信号のコヒーレンスに基づく心臓壁領域同定2009

    • Author(s)
      高橋広樹, 長谷川英之, 金井浩
    • Journal Title

      超音波医学 36

      Pages: 679-681

    • NAID

      10026312212

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Journal Article] Impact of Lifestyle-Related Diseases on Carotid Arterial Wall Elasticity as Evaluated by an Ultrasonic Phased-Tracking Method in Japanese Subjects2009

    • Author(s)
      Toshio Yamagishi, Makoto Kato, Yoshiro Koiwa, Hideyuki Hasegawa, Hiroshi Kanai
    • Journal Title

      Journal of Atherosclerosis and Thrombosis 16

      Pages: 782-791

    • NAID

      10026144266

    • Related Report
      2009 Annual Research Report
    • Peer Reviewed
  • [Presentation] Improved Imaging of the Carotid Artery in the Short-Axis Plane by Using Multi-Element Diverging Beam from a Linear Array Transducer2011

    • Author(s)
      Akinlolu Ponnle, Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      16th International Symposium of 2007 Tohoku University Global COE Program Global Nano-Biomedical Engineering Education and Research Network Centre
    • Place of Presentation
      Sendai
    • Year and Date
      2011-03-22
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Basic Study on Accurate Estimation of Surface Roughness Using Ultrasonic RF Echo for Application to Luminal Surface of Arterial Wall2010

    • Author(s)
      Kosuke Kitamura, Hideyuki Hasegawa, and Hiroshi Kanai
    • Organizer
      4th East Asian Pacific Student Workshop on Nano-Biomedeical Engineering
    • Place of Presentation
      Singapore, Singapore
    • Year and Date
      2010-12-15
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Blood Flow Stream Line Imaging by Direct Visualization of Echo Trajectories2010

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      IEEE 2010 International Ultrasonics Symposium
    • Place of Presentation
      San Diego, USA
    • Year and Date
      2010-10-13
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 心血管系の高速超音波イメージング2010

    • Author(s)
      長谷川英之, 金井 浩
    • Organizer
      電子情報通信学会2010 年ソサイエティ大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-17
    • Related Report
      2010 Final Research Report
  • [Presentation] 心血管系の高速超音波イメージング2010

    • Author(s)
      長谷川英之, 金井浩
    • Organizer
      電子情報通信学会2010年ソサイエティ大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-17
    • Related Report
      2010 Annual Research Report
  • [Presentation] 球面拡散超音波ビームを用いた高速心臓断層法2010

    • Author(s)
      長谷川英之, 金井 浩
    • Organizer
      日本音響学会2010年秋季研究発表会
    • Place of Presentation
      大阪
    • Year and Date
      2010-09-16
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Estimation of Scatterer's Size by Normalized Power Spectrum of High-Frequency Ultrasonic RF Echo for Assessment of Red Blood Cellaggregation2010

    • Author(s)
      Taku Fukushima, Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      7th International Conference on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      Matsushima
    • Year and Date
      2010-09-15
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Flow-Mediated Change in Viscoelastic Property of Radial Arterial Wall Byaccurate Detection of Arterial Wall Boundaries2010

    • Author(s)
      Kazuki Ikeshita, Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      7th International Conference on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      Matsushima
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Two-Dimensional Ultrasonic Measurement of Heart Wall Motion at Hightemporal and Spatial Resolutions2010

    • Author(s)
      Yasunori Honjo, Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      7th International Conference on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      Matsushima
    • Year and Date
      2010-09-14
    • Related Report
      2010 Final Research Report
  • [Presentation] Very High Frame Rate Imaging of Cardiovascular Tissues2010

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      7th International Conference on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      Matsushima
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Two-Dimensional Ultrasonic Measurement of Heart Wall Motion at High temporal and Spatial Resolutions2010

    • Author(s)
      Yasunori Honjo, Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      7th International Conference on Ultrasonic Biomedical Microscanning
    • Place of Presentation
      Matsushima
    • Year and Date
      2010-09-14
    • Related Report
      2010 Annual Research Report
  • [Presentation] 球面拡散ビームを用いた高速超音波心臓断層法2010

    • Author(s)
      長谷川英之, 金井 浩
    • Organizer
      電子通信情報学会応用音響研究会
    • Place of Presentation
      東北大学
    • Year and Date
      2010-08-10
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] High Frame Rate Cardiovascular Ultrasonography2010

    • Author(s)
      Hideyuki Hasegawa and Hiroshi Kanai
    • Organizer
      第49回日本生体工学会大会
    • Place of Presentation
      大阪
    • Year and Date
      2010-06-26
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] 超音波信号の位相偏移と位相変化率の同時推定によるラテラル変位計測2010

    • Author(s)
      長谷川英之, 金井 浩
    • Organizer
      日本超音波医学会第83回学術集会
    • Place of Presentation
      京都
    • Year and Date
      2010-05-30
    • Related Report
      2010 Annual Research Report 2010 Final Research Report
  • [Presentation] Evaluation of Transient Change in Viscoelasticity of Arterial Wall during Flow-Mediated Dilation2010

    • Author(s)
      Hiroshi Kanai, Hideyuki Hasegawa, Kazuki Ikeshita
    • Organizer
      12th International Symposium of 2007 Tohoku University Global COE Program Global Nano-Biomedical Engineering Education and Research Network Centre
    • Place of Presentation
      Sendai
    • Year and Date
      2010-03-27
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Artery-Wall Elasticity Imaging with Ultrasound2010

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      5rd International Symposium on Medical, Bio- and Nano-Electronics in Sendai
    • Place of Presentation
      Sendai
    • Year and Date
      2010-02-24
    • Related Report
      2010 Final Research Report
  • [Presentation] Artery-Wall Elasticity Imaging with Ultrasound2010

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      5rd International Symposium on Medical, Bio-and Nano-Electronics in Sendai
    • Place of Presentation
      Sendai
    • Year and Date
      2010-02-24
    • Related Report
      2009 Annual Research Report
  • [Presentation] Vascular Elasticity Imaging with Transcutaneous Ultrasound2010

    • Author(s)
      Hideyuki Hasegawa and Hiroshi Kanai
    • Organizer
      12th International Symposium on Advanced Biomedical Ultrasound
    • Place of Presentation
      Sendai
    • Year and Date
      2010-02-23
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Carotid Artery Elasticity Using the Phased-Tracking Method Is Useful as a Risk Factor for Coronary Artery Disease2009

    • Author(s)
      Yukiyo Ogata, Yukiya Miyachi, Kazushi Manaka, Hideyuki Hasegawa, Hiroshi Kanai, Koichi Itoh
    • Organizer
      EUROSON 2009
    • Place of Presentation
      Edinburgh, United Kingdom
    • Year and Date
      2009-12-06
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] In Vivo Measurements of Change in Viscoelasticity of Arterial Wall during The Flow-Mediated Dilation2009

    • Author(s)
      Hiroshi Kanai, Hideyuki Hasegawa, Kazuki Ikeshita
    • Organizer
      ASME 2009 International Mechanical Engineering Congress & Exposition IMECE2009
    • Place of Presentation
      Lake Buena Vista, USA
    • Year and Date
      2009-11-18
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] Lateral Motion Estimator for Measurement of Artery-Wall Displacement2009

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      IEEE 2009 International Ultrasonics Symposium
    • Place of Presentation
      Roma, Italy
    • Year and Date
      2009-09-22
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Presentation] High Frame Rate Ultrasonic Imaging of Artery-Wall Strain and Blood Flow2009

    • Author(s)
      Hideyuki Hasegawa, Hiroshi Kanai
    • Organizer
      10th International Symposium of 2007 Tohoku University Global COE Program Global Nano-Biomedical Engineering Education and Research Network Centre
    • Place of Presentation
      Christchurch, New Zealand
    • Year and Date
      2009-04-17
    • Related Report
      2010 Final Research Report 2009 Annual Research Report
  • [Book] ano-Biomedical Engineering 2009 129-1382009

    • Author(s)
      Hideyuki Hasegawa, Kentaro Tsuzuki, Masataka Ichiki, Fumiaki Tezuka, Hiroshi Kanai
    • Publisher
      Imperial College Press
    • Related Report
      2010 Final Research Report
  • [Book] Nano-Biomedical Engineering 20092009

    • Author(s)
      Takami Yamaguchi
    • Total Pages
      469
    • Publisher
      Imperial College Press
    • Related Report
      2009 Annual Research Report

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Published: 2009-04-01   Modified: 2016-04-21  

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