Development of bio-actuator constructed by magnetic force-based tissue engineering
| Project/Area Number |
21686079
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biofunction/Bioprocess
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| Research Institution | Kyushu University |
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Principal Investigator |
ITO Akira Kyushu University, 大学院・工学研究院, 准教授 (60345915)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
|
| Budget Amount *help |
¥15,340,000 (Direct Cost: ¥11,800,000、Indirect Cost: ¥3,540,000)
Fiscal Year 2010: ¥7,280,000 (Direct Cost: ¥5,600,000、Indirect Cost: ¥1,680,000)
Fiscal Year 2009: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
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| Keywords | ティッシュエンジニアリング / 磁性ナノ粒子 / バイオアクチュエータ / 骨格筋 / 筋芽細胞 / 筋組織 / アクチュエータ / 磁性粒子 / リポソーム / マグネタイト |
|---|
| Research Abstract |
If an artificial skeletal muscle can be applied as an actuator, it may exhibit high energy conversion efficiency. In this study, we successfully constructed three-dimensional tissue-like structures composed of myoblast cells by using a magnetic force-based tissue engineering technique. The tissue contracted rhythmically in response to electrical pulses. Moreover, we constructed genetically engineered myoblast cells to promote their performance as bio-actuator.
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Report
(3 results)
Research Products
(33 results)
