| Budget Amount *help |
¥27,170,000 (Direct Cost: ¥20,900,000、Indirect Cost: ¥6,270,000)
Fiscal Year 2011: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2010: ¥8,710,000 (Direct Cost: ¥6,700,000、Indirect Cost: ¥2,010,000)
Fiscal Year 2009: ¥9,750,000 (Direct Cost: ¥7,500,000、Indirect Cost: ¥2,250,000)
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| Research Abstract |
In Drosophila development, male genitalia performs 360o clockwise rotation as it forms, but L/R axis of genitalia is deformed if the rotation is incompletely stopped. Imaging analysis reveals that full rotation of genitalia is required the two steps movement of collective cells in epithelial sheet surrounding genitalia. We found that the secondary rotation that was initiated by apoptosis accelerated the primary rotation to adjust the speed of morphogenesis for the developmental time window.
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