• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to previous page

The Development of Normothermic Perfusion Preservation and"Post-conditioning"Methods in Liver Transplantation

Research Project

Project/Area Number 21689035
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field General surgery
Research InstitutionKyoto University

Principal Investigator

HATA Koichiro  Kyoto University, 医学研究科, 助教 (90523118)

Project Period (FY) 2009 – 2010
Project Status Completed (Fiscal Year 2010)
Budget Amount *help
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2010: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2009: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
Keywords灌流保存 / 肝移植 / ADAMTS13 / 臓器移植 / 生体肝移植 / 臓器保存
Research Abstract

In this study, we developed a pressure controlled perfusion preservation system, and evaluated the "Post-conditioning" effects in perfusion preservation with Isolated Perfused Rat Liver. It is plausible that normothermic perfusion preservation may preserve/improve the liver function better than cold storage, which is the gold standard preservation method, with protecting hepatic sinusoids.

Report

(3 results)
  • 2010 Annual Research Report   Final Research Report ( PDF )
  • 2009 Annual Research Report
  • Research Products

    (10 results)

All 2011 2010

All Journal Article (8 results) (of which Peer Reviewed: 8 results) Presentation (2 results)

  • [Journal Article] Thrombotic microangiopathy-likedisorder after living-donor livertrans plantation2011

    • Author(s)
      Hori T, Kaido T, Hata K, et al(23人中7番目)
    • Journal Title

      A single-center experiencein Japan. World J Gastroenterol. 17(14)

      Pages: 57-1848

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Recurrence of HepatocellularCarcinoma after Living Donor LiverTransplantation2011

    • Author(s)
      Kaido T, Mori A, Hata K, et al(7人中4番目).
    • Journal Title

      What is the CurrentOptimal Approach to Prevent Recurrence?World J Surg. 35(6)

      Pages: 9-1355

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Posttransplant bacteremia inadult living donor liver transplantrecipients.2010

    • Author(s)
      Iida T, Kaido T, Hata K, et al(10人中5番目)
    • Journal Title

      Liver Transpl. 16(12)

      Pages: 85-1379

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of enteral nutrition usinga new immuno-modulating diet after livertransplantation.2010

    • Author(s)
      Kaido T, Mori A, Hata K, et al(8人中4番目)
    • Journal Title

      Hepato gastroen terology. 57(104)

      Pages: 5-1522

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Impact of pretransplantnutritional status in patients undergoingliver transplantation.2010

    • Author(s)
      Kaido T, Mori A, Hata K, et al(9人中6番目)
    • Journal Title

      Hepatogastroenterology. 57(104)

      Pages: 92-1489

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Liver transplantation forcongenital biliary dilatation: asingle-center experience.2010

    • Author(s)
      Hori T, Oike F, Hata K, et al(17人中5番目)
    • Journal Title

      Dig Surg. 27(6)

      Pages: 492-501

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] Comprehensive and innovativetechniques for liver transplantation inrats: a surgical guide.2010

    • Author(s)
      Hori T, Nguyen JH, Hata K, et al(31人中18番目)
    • Journal Title

      World JGastroenterol. 16(25)

      Pages: 32-3120

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Journal Article] The rare insertion of b4 withtrifurcated portal vein in live donor.2010

    • Author(s)
      Iida T, Kaido T, Hata K, et al(10人中5番目)
    • Journal Title

      Transplantation. 89(9)

      Pages: 4-1163

    • Related Report
      2010 Final Research Report
    • Peer Reviewed
  • [Presentation] ADAMTS13, von Willebrand factorcleaving protease, activity and livergraft preservation; -how to reduce therisk for thrombotic microangiopathy-2011

    • Author(s)
      Hirokazu Tanaka, Koichiro Hata
    • Organizer
      the 46th annual European Society forSurgical Research congress
    • Place of Presentation
      Aachen, Germany
    • Year and Date
      2011-05-28
    • Related Report
      2010 Final Research Report
  • [Presentation] ADAMTS13, von Willebrand factor cleaving protease, activity and liver graft preservation ; how to reduce the risk for Thrombotic microangiopathy?2011

    • Author(s)
      H.Tanaka, K.Hata, et al.
    • Organizer
      46th Congress of the European Society for Surgical Research
    • Place of Presentation
      Aachen, Germany
    • Related Report
      2010 Annual Research Report

URL: 

Published: 2009-04-01   Modified: 2016-04-21  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi