The Development of Normothermic Perfusion Preservation and"Post-conditioning"Methods in Liver Transplantation
| Project/Area Number |
21689035
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| Research Category |
Grant-in-Aid for Young Scientists (A)
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| Allocation Type | Single-year Grants |
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| Research Field |
General surgery
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| Research Institution | Kyoto University |
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Principal Investigator |
HATA Koichiro Kyoto University, 医学研究科, 助教 (90523118)
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| Project Period (FY) |
2009 – 2010
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| Project Status |
Completed (Fiscal Year 2010)
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| Budget Amount *help |
¥18,200,000 (Direct Cost: ¥14,000,000、Indirect Cost: ¥4,200,000)
Fiscal Year 2010: ¥8,060,000 (Direct Cost: ¥6,200,000、Indirect Cost: ¥1,860,000)
Fiscal Year 2009: ¥10,140,000 (Direct Cost: ¥7,800,000、Indirect Cost: ¥2,340,000)
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| Keywords | 灌流保存 / 肝移植 / ADAMTS13 / 臓器移植 / 生体肝移植 / 臓器保存 |
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| Research Abstract |
In this study, we developed a pressure controlled perfusion preservation system, and evaluated the "Post-conditioning" effects in perfusion preservation with Isolated Perfused Rat Liver. It is plausible that normothermic perfusion preservation may preserve/improve the liver function better than cold storage, which is the gold standard preservation method, with protecting hepatic sinusoids.
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Report
(3 results)
Research Products
(10 results)
