Clarification of mechanisms for hierarchical gene expression in RNA world and its application
| Project/Area Number |
21689049
|
|---|
| Research Category |
Grant-in-Aid for Young Scientists (A)
|
| Allocation Type | Single-year Grants |
|---|
| Research Field |
Pathobiological dentistry/Dental radiology
|
|---|
| Research Institution | Nagasaki University |
|---|
Principal Investigator |
MORI Ryoichi 長崎大学, 大学院・医歯薬学総合研究科, 助教 (30509310)
|
|---|
| Project Period (FY) |
2009 – 2011
|
| Project Status |
Completed (Fiscal Year 2011)
|
| Budget Amount *help |
¥26,260,000 (Direct Cost: ¥20,200,000、Indirect Cost: ¥6,060,000)
Fiscal Year 2011: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2010: ¥6,500,000 (Direct Cost: ¥5,000,000、Indirect Cost: ¥1,500,000)
Fiscal Year 2009: ¥13,260,000 (Direct Cost: ¥10,200,000、Indirect Cost: ¥3,060,000)
|
|---|
| Keywords | 免疫 / 炎症 / microRNA / 次世代シークエンサー / 皮膚創傷治癒 / miRNA / 組織修復 / アンチセンスオリゴ / 線維化 / DNAアレイ / 次世代シーケンサー |
|---|
| Research Abstract |
Inflammation-related miRNAs might be involved in regulation of inflammatory response and tissue fibrosis. However, these genes have not been identified yet. In the present study, we identified wound-related known and unknown miRNAs using next generation sequencing. Then we identified inflammation-related miRNAs and clarified its functions using histological, cellular and molecular biological, and imaging analysis in vivo and in vitro.
|
Report
(4 results)
Research Products
(29 results)
-
-
-
-
-
-
-
-
-
-
[Journal Article] FoxO1 is involved in the antineoplastic effect of calorie restriction2010
Author(s)
Yamaza H, Komatsu T, Wakita S, Kijogi C, Park S, Hayashi H, Chiba T, Mori R, Furuyama T, Mori N, Shimokawa I
-
Journal Title
Aging Cell
Volume: 9
Pages: 372-382
NAID
Related Report
Peer Reviewed
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
